Case Report
Volume: 2 | Issue: 2 | Published: Jan 01, 1970 | Pages: 50 - 54 | DOI: 10.24911/ejmcr/2/19
Acute Fibrinous and Organizing Pneumonia associated to hematological malignancy: a case report
Authors: Filipa Ferreira Pereira , Mario Santos , Margarida Freitas Silva
Article Info
Authors
Filipa Ferreira Pereira
Medical Oncology Department, Instituto Portugues de Oncologia do Porto, Portugal, Department of Internal Medicine, Centro Hospitalar de Sao Joao E.P.E., Porto, Portugal
Mario Santos
Department of Internal Medicine, Centro Hospitalar de Sao Joao E.P.E., Porto, Portugal, Department of Internal Medicine, Centro Hospitalar de Sao Joao E.P.E., Porto, Portugal
Margarida Freitas Silva
Department of Internal Medicine, Centro Hospitalar de Sao Joao E.P.E., Porto, Portugal
Publication History
Received: March 24, 2018
Revised: April 29, 2018
Accepted: May 02, 2018
Published: January 01, 1970
Abstract
The acute fibrinoid and organizing pneumonia (AFOP) is an histophatological pattern featured for the presence of intra-alveolar fibrin and organizing pneumonia (1). AFOP is an entity that can be either idiopathic or associated with several clinical conditions, including infectious diseases, drug interactions and cancer. No specific treatment exists for AFOP but an excellent response to steroids therapy is observed. AFOP is still a not well understood entity and is defined with a distinct histological pattern that can appear adjacent to other entities, including hematologic malignancies. A 55-year-old man was admitted in hospital with pneumonia diagnosis, that had no response to antibiotics, but an excellent response to steroids. The lung biopsy supported the diagnosis of AFOP.
Keywords: Organizing pneumonia, fibrin, hematological malignancy, glucocorticoids
