Case Report
Volume: 2 | Issue: 2 | Published: Jan 01, 1970 | Pages: 55 - 58 | DOI: 10.24911/ejmcr/2/14
Cefixime-induced hepatotoxicity and acute renal failure: a case report
Authors: Ali Abdu Al Haboob
Article Info
Authors
Ali Abdu Al Haboob
Pediatrics Department, College of Medicine and King Khalid University Hospital (KKUH), King Saud University, Riyadh, Saudi Arabia
Publication History
Received: January 28, 2018
Revised: March 12, 2018
Accepted: April 04, 2018
Published: January 01, 1970
Abstract
Background: Cefixime is widely used in treating infections in children, and it can commonly cause minor gastrointestinal adverse effects. However, hepatotoxicity and acute renal failure are among the rarely reported serious adverse drug reactions of cefixime and other cephalosporins. Case Presentation: We report the case of a 7-month-old infant who was previously well but was admitted to the pediatric intensive care unit as she developed acute onset hepatic and renal failure two days after cefixime treatment. Her liver enzymes were more than 5-times the upper normal limit and her kidney function deteriorated acutely and rapidly over a short period, with evident acute renal parenchymal disease on abdominal ultrasound. Conclusion: Given the nature of rapid resolution of all organ-related insults and no other confirmed diagnosis and with the support of Naranjo and Roussel Uclaf Causality Assessment Method scales, this is probably the first case of cefixime-induced hepatotoxicity and acute renal failure.
Keywords: cephalosporin, hepatotoxicity, renal failure, case report
Pubmed Style
Ali Abdu Al Haboob. Cefixime-induced hepatotoxicity and acute renal failure: a case report. EJMCR. 1970; 01 (January 1970): 55-58. doi:10.24911/ejmcr/2/14
Web Style
Ali Abdu Al Haboob. Cefixime-induced hepatotoxicity and acute renal failure: a case report. https://ejmcr.com/articles/1570 [Access: December 03, 2024]. doi:10.24911/ejmcr/2/14
AMA (American Medical Association) Style
Ali Abdu Al Haboob. Cefixime-induced hepatotoxicity and acute renal failure: a case report. EJMCR. 1970; 01 (January 1970): 55-58. doi:10.24911/ejmcr/2/14
Vancouver/ICMJE Style
Ali Abdu Al Haboob. Cefixime-induced hepatotoxicity and acute renal failure: a case report. EJMCR. (1970), [cited December 03, 2024]; 01 (January 1970): 55-58. doi:10.24911/ejmcr/2/14
Harvard Style
Ali Abdu Al Haboob (1970) Cefixime-induced hepatotoxicity and acute renal failure: a case report. EJMCR, 01 (January 1970): 55-58. doi:10.24911/ejmcr/2/14
Chicago Style
Ali Abdu Al Haboob. "Cefixime-induced hepatotoxicity and acute renal failure: a case report." 01 (1970), 55-58. doi:10.24911/ejmcr/2/14
MLA (The Modern Language Association) Style
Ali Abdu Al Haboob. "Cefixime-induced hepatotoxicity and acute renal failure: a case report." 01.January 1970 (1970), 55-58. Print. doi:10.24911/ejmcr/2/14
APA (American Psychological Association) Style
Ali Abdu Al Haboob (1970) Cefixime-induced hepatotoxicity and acute renal failure: a case report. , 01 (January 1970), 55-58. doi:10.24911/ejmcr/2/14