Case Report
Volume: 4 | Issue: 3 | Published: Jan 01, 1970 | Pages: 103 - 106 | DOI: 10.24911/ejmcr/1731577849668
Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report
Authors: Iftikhar Ahmad , Mehjabeen Marri , Sadaf Noor
Article Info
Authors
Iftikhar Ahmad
Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan
Mehjabeen Marri
Center for Nuclear Medicine and Radiotherapy (CENAR), Quetta, Pakistan
Sadaf Noor
Shukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
Publication History
Received: January 01, 2020
Revised: March 10, 2020
Accepted: March 27, 2020
Published: January 01, 1970
Abstract
Background: Extra-nodal diffuse large B-cell lymphoma (DLBCL) is an exceedingly uncommon disease. Case Presentation: Herein, we report a case of a 60-year-old male patient who presented with DLBCL of the left leg, and involving the gastrocnemius muscle. The patient received CHOP regimen-based neoadjuvant chemotherapy (i.e., six courses of cyclophosphamide, doxorubicin, vincristine, and prednisone), which reduced the tumor size to the point where complete resection became possible. Afterward, the tumor was completely resected. The tumor bed subsequently received conventional radiotherapy (i.e., 36 Gy/18 fractions). The patient is being followed up regularly and has remained disease-free for over 1.5 years. Conclusion: This case demonstrates that DLBCL is an aggressive malignancy but can be effectively managed with multi-modality treatment strategy.
Keywords: Diffuse large B-cell lymphoma, CHOP regimen, R-CHOP regimen, non-Hodgkins lymphoma, radiotherapy, green
