Case Report

Volume: 2 | Issue: 2 | Published: May 29, 2018 | Pages: 42 - 44 | DOI: 10.24911/ejmcr/2/18

Life-threatening hypercalcemia and primary plasma cell leukemia: a case report of a rare presentation


Authors: Abdelaziz Khalloufi , Ilyas El Kassimi , Abdelghafour Elkoundi , Zineb Taki , Mohamed Hassani , Hicham Eddou


Article Info

Authors

Abdelaziz Khalloufi

Hematology laboratory, Military Hospital Moulay Ismail, Meknes, Morocco

Ilyas El Kassimi

Internal medicine department, Military Hospital Mohammed V, Rabat, Morocco

Abdelghafour Elkoundi

Anesthesiology and intensive care department, Military Hospital Mohammed V, Rabat, Morocco.

Zineb Taki

Hematology laboratory, Military Hospital Moulay Ismail, Meknes, Morocco.

Mohamed Hassani

Nephrology department, Military Hospital Moulay Ismail, Meknes, Morocco

Hicham Eddou

Clinical Hematology department, Military Hospital Moulay Ismail, Meknes, Morocco.

Publication History

Received: April 19, 2018

Accepted: April 23, 2018

Published: May 29, 2018


Abstract


Background: Hypercalcemia can cause a multitude of nonspecific symptoms, although it can manifest as a life-threatening metabolic emergency. Several underlying causes should be considered in the emergency department (ED). Life-threatening hypercalcemia as the initial manifestation of primary plasma cell leukemia (pPCL) is quite unusual. Case presentation: We present a case of a 63-year-old man who presented to the emergency department with symptomatic hypercalcemia and acute renal failure that was linked to a diagnosis of pPCL. Despite adequate treatment, his course was associated with significant morbidity and was severe enough to threaten his life. Conclusion: Severe hypercalcemia with particular attention to the peripheral blood smear should alert physicians to this highly deadly entity.

Keywords: Primary plasma cell leukemia, hypercalcemia, peripheral blood smear, poor prognosis, emergency, case report