Case Report
Volume: 3 | Issue: 3 | Published: Jan 01, 1970 | Pages: 112 - 115 | DOI: 10.24911/ejmcr/173-1555632293
Rivaroxaban-induced skin necrosis: a case report
Authors:
Mosaad Abelhameed Soliman
, Khalid AbdelAziz Mowafy
, Nashaat Abdrabo Elsaadany
, Rana Ibraheem Soliman
, Sameh Ibraheem Awad
, Reem Ibraheem Soliman
Article Info
Authors
Mosaad Abelhameed Soliman
Head of Vascular Surgery Department, Faculty of Medicine, Mansoura University, Egypt
Khalid AbdelAziz Mowafy
Vascular Surgery Department, Faculty of Medicine, Mansoura University
Nashaat Abdrabo Elsaadany
Assistant Lecturer of Vascular Surgery, Faculty of Medicine, Mansoura University, Egypt
Rana Ibraheem Soliman
Consultant Dermatology, Faculty of Medicine, Mansoura University, Egypt
Sameh Ibraheem Awad
Assistant Lecturer of Vascular Surgery, Faculty of Medicine, Mansoura University, Egypt
Reem Ibraheem Soliman
Assistant Lecturer, Department of Vascular Surgery, Faculty of Medicine, Mansoura University, Egypt
Publication History
Received: April 25, 2019
Revised: August 01, 2019
Accepted: November 01, 2019
Published: January 01, 1970
Abstract
Background: Even though rivaroxaban has been mainly associated with hemorrhage-related adverse effects, rivaroxaban-induced skin necrosis has received less attention or went unrecognized. Little has been documented about hypersensitivity reactions caused by the treatment with rivaroxaban. Case Presentation: This paper reports a skin necrosis with an apparent similarity to skin adverse events caused by the different anticoagulants. It happened in a 30-year-old female patient during rivaroxaban treatment. The correlation of the skin lesions to the used drug was made by the act of repeated discontinuation and reuse of rivaroxaban and the noticed remission and exacerbation of skin necrosis. Conclusion: This case highlights the vigilance required by healthcare in recognizing potential adverse effects of newly marketed drugs and in making medication changes whenever necessary.
Keywords: Rivaroxaban, adverse effects, anaphylaxis, hypersensitivity, skin necrosis, green
