Case Report

Volume: 4 | Issue: 11 | Published: Nov 14, 2020 | Pages: 387 - 389 | DOI: 10.24911/ejmcr/173-1590635137

Beckwith-Wiedemann syndrome and pregnancy - a case report


Authors: Priyanka H. Krishnaswamy , Louise Howarth , Rohit Arora


Article Info

Authors

Priyanka H. Krishnaswamy

Registrar in Obstetrics and Gynaecology and Honorary Clinical Lecturer, Queen Elizabeth University Hospital, Govan, Glasgow

Louise Howarth

Registrar in Obstetrics and Gynaecology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, United Kingdom

Rohit Arora

Consultant Obstetrician and Gynaecologist and Honorary Senior Clinical lecturer, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, United Kingdom

Publication History

Received: May 31, 2020

Accepted: September 25, 2020

Published: November 14, 2020


Abstract


Background: Pregnant mothers with babies diagnosed to have Beckwith-Wiedemann syndromes (BWSs) have been reported in very few case reports in the literature. Case Presentation: This case report describes the course of two pregnancies in a woman with BWS. The main metabolic issues encountered were recurrent episodes of hypoglycemia and suspected diabetes insipidus in pregnancy. Labor and delivery were uneventful, but she had significant secondary postpartum hemorrhage on both occasions. Conclusion: This syndrome has not been studied in the antenatal period and its course in pregnancy is not well known. We discuss possible complications that women with this syndrome could present with, the need for blood glucose and urine monitoring, a multidisciplinary approach, and close liaison with medical colleagues to identify and treat metabolic complications early.

Keywords: Beckwith-Wiedemann, pregnancy, complications, case report, green