Case Report

Volume: 8 | Issue: 2 | Published: Apr 30, 2024 | Pages: 37 - 40 | DOI: 10.24911/ejmcr.173-1706128578

Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report


Authors: Julie Tuypens , Jaro Van Zande , Klaas Van Den Heede orcid logo , Sam Van Slycke orcid logo


Article Info

Authors

Julie Tuypens

Department of General and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium

Jaro Van Zande

Department of General and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium

Klaas Van Den Heede

Department of General and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium

orcid logo ORCID

Sam Van Slycke

Department of General and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium

orcid logo ORCID

Publication History

Received: January 24, 2024

Revised: February 18, 2024

Accepted: March 29, 2024

Published: April 30, 2024


Abstract


Background: Gallbladder metastasis from renal cell carcinoma (RCC) is extremely rare. Case Presentation: We present a case of metastasis of clear cell carcinoma to the gallbladder, mimicking acute cholecystitis on clinical exam, in an 80-year-old man 24 years after radical nephrectomy. Ultrasound showed an image compatible with acute cholecystitis with sludge in the gallbladder. An elective cholecystectomy was performed with an uneventful postoperative course. Histopathologic examination revealed a metastasis of clear-cell renal cell carcinoma. The clinical presentation of acute cholecystitis can mask an RCC metastasis to the gallbladder, even several years after initial nephrectomy. This makes qualitative anatomopathological examination essential, especially with a neoplasia in the medical history. Gallbladder metastasis from RCC is not necessarily linked to a poor outcome. A cholecystectomy is recommended whenever possible. Conclusion: This case highlights the importance of considering metastatic disease in the differential diagnosis of gallbladder masses and acute cholecystitis, even in patients with a history of treated primary tumors.

Keywords: Case Report, Gallbladder, Metastasis, Renal Cell Carcinoma, green