Case Report

Volume: 5 | Issue: 1 | Published: Jan 22, 2021 | Pages: 4 - 6 | DOI: 10.24911/ejmcr/173-1583260504

Basaloid carcinoma of urinary bladder: an uncommon type of bladder cancer: a case report


Authors: Fayek Taha , Anne Durlach , Stephane Larre


Article Info

Authors

Fayek Taha

Resident, Service d’urologie du CHU de Reims, France

Anne Durlach

CHU de Reims 1, rue du General Koenig 51100 REIMS France

Stephane Larre

Service d’urologie du CHU de Reims, France

Publication History

Received: March 03, 2020

Revised: November 23, 2020

Accepted: November 23, 2020

Published: January 22, 2021


Abstract


Background: The basaloid carcinoma has not been previously described in the urinary bladder. Case presentation: A 61-year-old man presented with hematuria. The patient had a history of skin tumor with 37 basal cell carcinomas, which had often been treated with surgical excision. The cystoscopy showed a superficial 6 mm papillary lesion. A transurethral resection (TUR) instillation was performed, and the histological analysis revealed an invasive basaloid carcinoma pT1. Because of this uncommon histological aspect, a second Look TUR was conducted and showed no tumor and was followed by an intravesical Bacillus Calmette-Guerin therapy. Knowing the patient presented two major aspects of the Gorlin Syndrome, a genetic analysis of patched mutation had been done but showed no mutation of the gene. After 5 years of cystoscopy follow-up, the patient presented no recurrence of the tumor in the bladder. Conclusion: The basaloid carcinoma is an exceptional variant tumor in the urinary bladder.

Keywords: Basaloid carcinoma, urinary bladder, PTCH gene, urinary bladder neoplasm, histological variant, green