Case Report
Volume: 5 | Issue: 1 | Published: Jan 22, 2021 | Pages: 4 - 6 | DOI: 10.24911/ejmcr/173-1583260504
Basaloid carcinoma of urinary bladder: an uncommon type of bladder cancer: a case report
Authors: Fayek Taha , Anne Durlach , Stephane Larre
Article Info
Authors
Fayek Taha
Resident, Service durologie du CHU de Reims, France
Anne Durlach
CHU de Reims 1, rue du General Koenig 51100 REIMS France
Stephane Larre
Service d’urologie du CHU de Reims, France
Publication History
Received: March 03, 2020
Revised: November 23, 2020
Accepted: November 23, 2020
Published: January 22, 2021
Abstract
Background: The basaloid carcinoma has not been previously described in the urinary bladder. Case presentation: A 61-year-old man presented with hematuria. The patient had a history of skin tumor with 37 basal cell carcinomas, which had often been treated with surgical excision. The cystoscopy showed a superficial 6 mm papillary lesion. A transurethral resection (TUR) instillation was performed, and the histological analysis revealed an invasive basaloid carcinoma pT1. Because of this uncommon histological aspect, a second Look TUR was conducted and showed no tumor and was followed by an intravesical Bacillus Calmette-Guerin therapy. Knowing the patient presented two major aspects of the Gorlin Syndrome, a genetic analysis of patched mutation had been done but showed no mutation of the gene. After 5 years of cystoscopy follow-up, the patient presented no recurrence of the tumor in the bladder. Conclusion: The basaloid carcinoma is an exceptional variant tumor in the urinary bladder.
Keywords: Basaloid carcinoma, urinary bladder, PTCH gene, urinary bladder neoplasm, histological variant, green