Case Report
Volume: 6 | Issue: 7 | Published: Nov 21, 2022 | Pages: 119 - 122 | DOI: 10.24911/ejmcr/173-1650278347
Neuroendocrine tumor in a longstanding tailgut cyst: a case report
Authors: Mirella Pace , Raduan Ahmed Franca , Pasquale Cretella , Maria Michela Di Nuzzo , Roberto Peltrini , Michele D ambra , Maria Laura Del Basso De Caro , Maria Rosaria D Armiento
Article Info
Authors
Mirella Pace
Department of Biomorfological and Functional Sciences, University of Naples Federico II, Naples, Italy
Raduan Ahmed Franca
Department of Biomorfological and Functional Sciences, University of Naples Federico II, Naples, Italy
Pasquale Cretella
Department of Biomorfological and Functional Sciences, University of Naples Federico II, Naples, Italy
Maria Michela Di Nuzzo
Department of Public Health, University of Naples Federico II, Naples, Italy
Roberto Peltrini
Department of Public Health, University of Naples Federico II, Naples, Italy
Michele D ambra
Department of Public Health, University of Naples Federico II, Naples, Italy
Maria Laura Del Basso De Caro
Department of Biomorfological and Functional Sciences, University of Naples Federico II, Naples, Italy
Maria Rosaria D Armiento
Department of Public Health, University of Naples Federico II, Naples, Italy.
Publication History
Received: April 25, 2022
Revised: October 15, 2022
Accepted: October 15, 2022
Published: November 21, 2022
Abstract
Background: Retrocecal hamartomas are rare cystic lesions due to the persistence of the tailgut. Sometimes the epithelial or mesenchymal components of the cyst wall undergo neoplastic transformation, and, within them, carcinomas and sarcomas can develop. Case Presentation: We present the case of a multicystic lesion, discovered in a patient with perineal pain, which the imaging investigations have localized in the retrocecal space. The histological evaluation performed on his excisional biopsy demonstrates a retrocecal hamartoma harboring a neuroendocrine neoplasm. Conclusion: Tailgut cysts (TGC) are quite rare, only sometimes symptomatic, and infrequently, they also undergo a malignant transformation; in particular, the literature reviews report a higher frequency of adenocarcinomas. The differential diagnosis between lesions with different prognoses and pathogenesis that can develop in the retrocecal space requires a histological examination, which in some cases, becomes essential if we consider the potential for metastatic and local recurrence of any malignant neoplasm that arose in this site.
Keywords: Neuroendocrine tumor, retrorectal hamartoma, tail-gut, green
