Case Report
Volume: 6 | Issue: 1 | Published: Jan 01, 1970 | Pages: 11 - 16 | DOI: 10.24911/ejmcr/173-1622061632
A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge
Authors: Andrew Richardson , Claire Vincent
Article Info
Authors
Andrew Richardson
Trainee, Raigmore Hospital, Scotland, UK
Claire Vincent
Acute Medicine Consultant, Raigmore Hospital, Scotland, UK
Publication History
Received: August 06, 2021
Revised: September 02, 2021
Accepted: September 02, 2021
Published: January 01, 1970
Abstract
Background: Type 2 diabetes (T2DM) is becoming more prevalent worldwide and sodium-glucose co-transporter-2 (SGLT2) inhibitors are being increasingly used in its management. However, they have been associated with the serious complication of euglycemic diabetic ketoacidosis (EDKA). Case Presentation: A 51-year-old female on canagliflozin for T2DM presented with a 2-week history of vomiting and abdominal pain. With a blood glucose of 9.0 mmol/l, a diagnosis of diabetic ketoacidosis was at first overlooked and the patient was initially managed for pyelonephritis. However, a diagnosis of EDKA was subsequently reached on day 3 after a blood gas revealed a high anion gap metabolic acidosis with ketones of 3.9 mmol/l. Conclusion: This case demonstrates the diagnostic challenge posed by the atypical presentation of SGLT2 inhibitor-associated EDKA. Furthermore, it underlines the need for patient education concerning stopping these medications during illness and highlights how their association with urinary tract infections may further increase the risk of EDKA.
Keywords: Case report, diabetes, SGLT2 inhibitors, euglycemic diabetic ketoacidosis, medication related complication, green
Pubmed Style
Andrew Richardson, Claire Vincent. A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge. EJMCR. 1970; 01 (January 1970): 11-16. doi:10.24911/ejmcr/173-1622061632
Web Style
Andrew Richardson, Claire Vincent. A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge. https://ejmcr.com/articles/1081 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1622061632
AMA (American Medical Association) Style
Andrew Richardson, Claire Vincent. A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge. EJMCR. 1970; 01 (January 1970): 11-16. doi:10.24911/ejmcr/173-1622061632
Vancouver/ICMJE Style
Andrew Richardson, Claire Vincent. A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge. EJMCR. (1970), [cited December 25, 2024]; 01 (January 1970): 11-16. doi:10.24911/ejmcr/173-1622061632
Harvard Style
Andrew Richardson, Claire Vincent (1970) A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge. EJMCR, 01 (January 1970): 11-16. doi:10.24911/ejmcr/173-1622061632
Chicago Style
Andrew Richardson, Claire Vincent. "A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge." 01 (1970), 11-16. doi:10.24911/ejmcr/173-1622061632
MLA (The Modern Language Association) Style
Andrew Richardson, Claire Vincent. "A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge." 01.January 1970 (1970), 11-16. Print. doi:10.24911/ejmcr/173-1622061632
APA (American Psychological Association) Style
Andrew Richardson, Claire Vincent (1970) A case report of sodium glucose co-transporter 2 inhibitor associated euglycemic diabetic ketoacidosis: a diagnostic challenge. , 01 (January 1970), 11-16. doi:10.24911/ejmcr/173-1622061632