EJMCR |

Case Report

Volume: 6 | Issue: 1 | Published: Jan 30, 2022 | Pages: 5 - 10 | DOI: 10.24911/ejmcr/173-1621184951

Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature

Authors: Girish Kulkarni , Asad Abbas

Article Info

Authors

Girish Kulkarni

Department of Neurosurgery, Nottingham University, Hospital, Queens Medical Center, Nottingham, UK

Asad Abbas

Department of Neurosurgery, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK

Publication History

Received: May 16, 2021

Revised: June 25, 2021

Accepted: June 25, 2021

Published: January 30, 2022

Abstract

Background: The malignant transformation of vestibular schwannoma (VS) is a rare identity. We present a case of spontaneous transformation of VS and a short literature review. Case Presentation: A 41-year-old female had presented to us with vertigo, tinnitus, and hearing loss. She was diagnosed with left VS and underwent surgical resection. The initial histology was reported as benign grade 1 schwannoma. She subsequently presented to the hospital with hematoma in the tumor cavity after 4 and 5 months, respectively. Her repeat magnetic resonance imaging (MRI) showed growth of the residual tumor. She underwent a second translabyrinthine excision of the tumor. The histology from the second operation showed components of malignant transformation. One month postoperatively she suffered an acute decline in her conscious level. Repeat MRI demonstrated rapid regrowth of the tumor with further hemorrhage. In view of her rapid decline and perceived futility of further intervention and respecting her premorbid wishes, further escalation of therapy was deemed inappropriate. Conclusion: VS can transform into a malignant tumor even in the absence of radiation therapy. This may be considered in case of rapid regrowth of the tumor.

Keywords: Case report, vestibular schwannoma, malignant transformation, cerebellopontine angle tumor, green

Pubmed Style

Girish Kulkarni, Asad Abbas. Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature. EJMCR. 2022; 30 (January 2022): 5-10. doi:10.24911/ejmcr/173-1621184951

Web Style

Girish Kulkarni, Asad Abbas. Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature. https://ejmcr.com/articles/1080 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1621184951

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Girish Kulkarni, Asad Abbas. Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature. EJMCR. (2022), [cited December 25, 2024]; 30 (January 2022): 5-10. doi:10.24911/ejmcr/173-1621184951

Harvard Style

Girish Kulkarni, Asad Abbas (2022) Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature. EJMCR, 30 (January 2022): 5-10. doi:10.24911/ejmcr/173-1621184951

Chicago Style

Girish Kulkarni, Asad Abbas. "Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature." 30 (2022), 5-10. doi:10.24911/ejmcr/173-1621184951

MLA (The Modern Language Association) Style

Girish Kulkarni, Asad Abbas. "Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature." 30.January 2022 (2022), 5-10. Print. doi:10.24911/ejmcr/173-1621184951

APA (American Psychological Association) Style

Girish Kulkarni, Asad Abbas (2022) Spontaneous malignant transformation of vestibular schwannoma: a case report and review of the literature. , 30 (January 2022), 5-10. doi:10.24911/ejmcr/173-1621184951