EJMCR |

Case Report

Volume: 5 | Issue: 7 | Published: Jul 02, 2021 | Pages: 191 - 196 | DOI: 10.24911/ejmcr/173-1587876972

A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis

Authors: Karattuthodi Mohammed Salim , Ramsiya Saidalavi , Kainadan Fabin , Kizhissery Salman Faris , Aswathi Vijayan

Authors

Karattuthodi Mohammed Salim

Assistant Professor, Department of Pharmacy Practice, Al Shifa College of Pharmacy, Affiliated to Kerala University of Health Sciences, India

Ramsiya Saidalavi

PharmD Intern, Department of Pharmacy Practice, Al Shifa College of Pharmacy, Affiliated to Kerala University of Health Sciences, India

Kainadan Fabin

PharmD Intern, Department of Pharmacy Practice, Al Shifa College of Pharmacy, Affiliated to Kerala University of Health Sciences, India

Kizhissery Salman Faris

PharmD Intern, Department of Pharmacy Practice, Al Shifa College of Pharmacy, Affiliated to Kerala University of Health Sciences, India

Aswathi Vijayan

Junior Resident, Department of Radiodiagnosis, Government Medical College, Calicut, India

Publication History

Received: April 26, 2020

Revised: February 16, 2021

Accepted: May 07, 2021

Published: July 02, 2021

Abstract

Background: The fall of serum sodium concentration may happen in hyperemesis gravidarum and subsequently can result into hypotonic hyponatremia. This would cause water to move into the brain and develop cerebral edema manifested with neurologic symptoms. However, adaptive mechanism by brain would lower the cerebral volume to a normal range. On the other hand, rapid correction of chronic hyponatremia would damage the brain cells. The symptoms depicted because of rapid over correction of sodium is known as osmotic demyelination syndrome. Case Presentation: The pregnant lady with hyperemesis gravidarum went to severe hyponatremia. And further, she underwent dilatation and evacuation because of the intrauterine fetal death. The normal saline administered to correct the state of hyponatremia caused the patient to be in depression with catatonia and aphasia. The symptoms were correlated with osmotic demyelinolysis and the event was confirmed with magnetic resonance imaging of brain. Conclusion: The administration of sodium should be performed with utmost cautions and under the supervision of welltrained healthcare providers. Any sign or symptom of neurological abnormalities observed because of overcorrection should be considered seriously.

Keywords: Dyselectrolytemia, hyperemesis, hyponatremia, intrauterine fetal death, osmotic demyelinolysis, green

Pubmed Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan. A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis. EJMCR. 2021; 02 (July 2021): 191-196. doi:10.24911/ejmcr/173-1587876972

Web Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan. A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis. https://ejmcr.com/articles/1301 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1587876972

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan. A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis. EJMCR. (2021), [cited December 25, 2024]; 02 (July 2021): 191-196. doi:10.24911/ejmcr/173-1587876972

Harvard Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan (2021) A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis. EJMCR, 02 (July 2021): 191-196. doi:10.24911/ejmcr/173-1587876972

Chicago Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan. "A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis." 02 (2021), 191-196. doi:10.24911/ejmcr/173-1587876972

MLA (The Modern Language Association) Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan. "A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis." 02.July 2021 (2021), 191-196. Print. doi:10.24911/ejmcr/173-1587876972

APA (American Psychological Association) Style

Karattuthodi Mohammed Salim, Ramsiya Saidalavi, Kainadan Fabin, Kizhissery Salman Faris, Aswathi Vijayan (2021) A case report of pregnant lady with hyperemesis gravidarum that led to osmotic demyelinolysis. , 02 (July 2021), 191-196. doi:10.24911/ejmcr/173-1587876972