EJMCR. 2020; 4(2): 52-55

A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report

Authors: Taymmia Ejaz, Jamal Ahmed, Mahmood Malik, Yousaf Jamal.

ABSTRACT

Background: Influenza A H1N1 pdm09-associated neurological complications are rare, particularly in adults. This case report highlights one of the uncommon presentations associated with H1N1 pdm09 infection. Case Presentation: We present the case of a 38-year-old male who was admitted to the hospital primarily with respiratory manifestations and developed acute cerebellar ataxia during hospital stay, causing a diagnostic dilemma, as his cerebrospinal fluid analysis and magnetic resonance imaging brain were unremarkable. Throat swab real-time reverse transcriptase polymerase chain reaction (rRT-PCR) turned out positive for influenza A (H1N1) pdm09 virus strain and a nontypeable influenza A strain. He showed the resolution of cerebellar signs and a remarkable recovery on oseltamivir therapy. Based on the acute onset, positive RT-PCR and recovery on antiviral, a diagnosis of H1N1-associated cerebellitis was made. Conclusion: This report highlights an extremely rare complication of influenza infection with only five reported cases in adults and case series in children. Vigilance and a high index of suspicion for patients presenting with rapid onset neurological deterioration during pandemics and seasonal epidemics can prevent devastating sequelae.

Keywords:
Cerebellitis, influenza, cerebellar ataxia, influenza-associated encephalopathy, case report


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A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report


Authors
Taymmia Ejaz
Pulmonology Department, Military Hospital Rawalpindi, National University of Medical Sciences, Rawalpindi, Pakistan
PubMed articlesGoogle scholar articles

Jamal Ahmed
Pulmonology Department, Military Hospital Rawalpindi, National University of Medical Sciences, Rawalpindi, Pakistan
PubMed articlesGoogle scholar articles

Mahmood Malik
Pulmonology Department, Military Hospital Rawalpindi, National University of Medical Sciences, Rawalpindi, Pakistan
PubMed articlesGoogle scholar articles

Yousaf Jamal
Pulmonology Department, Military Hospital Rawalpindi, National University of Medical Sciences, Rawalpindi, Pakistan
PubMed articlesGoogle scholar articles


Correspondence to:
. Taymmia Ejaz, Pulmonology Department, Military Hospital Rawalpindi, National University of Medical Sciences, Rawalpindi, Pakistan.; taymmia.ejaz@gmail.com

Publication history
Received 29 Jan 2019
Revised 03 Dec 2019
Accepted 12 Feb 2020
Published online 03 Mar 2020
Published in print 12 Mar 2020

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Pubmed Style

Ejaz T, Ahmed J, Malik M, Jamal Y. A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. EJMCR. 2020; 4(2): 52-55. doi:10.24911/ejmcr/173-1548796037


Web Style

Ejaz T, Ahmed J, Malik M, Jamal Y. A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. https://www.ejmcr.com/?mno=28622 [Access: March 30, 2020]. doi:10.24911/ejmcr/173-1548796037


AMA (American Medical Association) Style

Ejaz T, Ahmed J, Malik M, Jamal Y. A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. EJMCR. 2020; 4(2): 52-55. doi:10.24911/ejmcr/173-1548796037


Vancouver/ICMJE Style

Ejaz T, Ahmed J, Malik M, Jamal Y. A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. EJMCR. (2020), [cited March 30, 2020]; 4(2): 52-55. doi:10.24911/ejmcr/173-1548796037


Harvard Style

Ejaz, T., Ahmed, . J., Malik, . M. & Jamal, . Y. (2020) A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. EJMCR, 4 (2), 52-55. doi:10.24911/ejmcr/173-1548796037


Turabian Style

Ejaz, Taymmia, Jamal Ahmed, Mahmood Malik, and Yousaf Jamal. 2020. A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. European Journal of Medical Case Reports, 4 (2), 52-55. doi:10.24911/ejmcr/173-1548796037


Chicago Style

Ejaz, Taymmia, Jamal Ahmed, Mahmood Malik, and Yousaf Jamal. "A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report." European Journal of Medical Case Reports 4 (2020), 52-55. doi:10.24911/ejmcr/173-1548796037


MLA (The Modern Language Association) Style

Ejaz, Taymmia, Jamal Ahmed, Mahmood Malik, and Yousaf Jamal. "A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report." European Journal of Medical Case Reports 4.2 (2020), 52-55. Print. doi:10.24911/ejmcr/173-1548796037


APA (American Psychological Association) Style

Ejaz, T., Ahmed, . J., Malik, . M. & Jamal, . Y. (2020) A rare case of H1N1 pdm09 infection with acute cerebellar syndrome - a case report. European Journal of Medical Case Reports, 4 (2), 52-55. doi:10.24911/ejmcr/173-1548796037


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