Case Report
Volume: 1 | Issue: 3 | Published: Jan 01, 1970 | Pages: 114 - 121 | DOI: 10.24911/ejmcr/1/28
Linezolid induced optic neuropathy, a serious yet reversible adverse effect: a case report
Authors: Ritesh Kumar Shah , Samir Lamichhane
Article Info
Authors
Ritesh Kumar Shah
1.Department of Ophthalmology, Childrens' hospital for eye, ENT and rehabilitation services (CHEERS), B.P. eye foundation, Nepal
Samir Lamichhane
2. Department of Clinical Pharmacology, Maharajgunj Medical Campus, Institute Of Medicine, Tribhuvan University, Nepal.
Publication History
Received: June 14, 2017
Accepted: July 04, 2017
Published: January 01, 1970
Abstract
Background: Linezolid like many other systemic drugs can cause reversible sight threatening adverse reaction. A proper causality assessment tool can help decide discontinuing a drug when an adverse event is suspected. Case presentation: We describe a case of progressive visual loss in a 28-year-old lady under long term linezolid for extensively drug resistant tuberculosis. A marked improvement in vision was seen on discontinuation of linezolid. Conclusion: A knowledge of visual monitoring in patients under long term linezolid therapy among physicians and ophthalmologists is important, especially in developing countries where infectious disease is still a problem and use of antimicrobials is hardly monitored.
Keywords: adverse effect, case report, linezolid, optic neuropathy, green
