Case Report

Volume: 4 | Issue: 1 | Published: Jan 03, 2020 | Pages: 9 - 12 | DOI: 10.24911/ejmcr/173-1549270214

Primary isolated amyloidosis of the urethra: a case report


Authors: Felix Kwizera , Philippe Uystepruyst , Renaud Bollens , Andre Gilles , Jean-Hubert Maquet


Article Info

Authors

Felix Kwizera

Department of Urology, Centre Hospitalier EpiCURA, Hornu, Belgium

Philippe Uystepruyst

Department of Urology, Centre Hospitalier EpiCURA, Hornu, Belgium

Renaud Bollens

Department of Urology, Centre Hospitalier EpiCURA, Hornu, Belgium

Andre Gilles

Department of Histopathology, Centre Hospitalier EpiCURA, Hornu, Belgium

Jean-Hubert Maquet

Department of Urology, Centre Hospitalier EpiCURA, Hornu, Belgium

Publication History

Received: March 21, 2019

Revised: July 29, 2019

Accepted: October 14, 2019

Published: January 03, 2020


Abstract


Background: Amyloidosis is a tissue protein deposition. Urethral amyloidosis is rare. Clinical presentation includes hematuria, obstructive urinary symptoms, urethritis-like symptoms, urethral discharge, or a palpable penile/urethral mass. The diagnosis is made by urethro-cystoscopy and biopsy. Case Presentation: We report the case of a 38-year-old man with a medical history of recurrent urinary tract infections, urethral discharge, and a palpable bulbar urethral mass. Urethral biopsies confirmed the urethral amyloidosis. The treatment was endoscopic urethral dilatation. Conclusion: Urethral amyloidosis is a rare condition and a challenging diagnosis. Urethroscopy is the best method for diagnosis. Biopsies should be done to exclude malignancy.

Keywords: Urethra, amyloidosis, genito-urinary amyloidosis, urinary tract infection, case report, green