Case Report

Volume: 4 | Issue: 9 | Published: Oct 13, 2020 | Pages: 323 - 326 | DOI: 10.24911/ejmcr/173-1595426123

A case report of primary gastric melanoma causing massive upper gastrointestinal bleeding in an adult


Authors: Azhar Perwaiz , Sankar Narayanan , Rashi Sharma , Amanjeet Singh


Article Info

Authors

Azhar Perwaiz

Associate Director of Esophago Gastric Surgery, Division of GI Surgery, GI Oncology, Minimal Access, and Bariatric Surgery, Medanta The Medicity, Haryana, India

Sankar Narayanan

Associate Consultant, Division of GI Surgery, GI Oncology, Minimal Access, and Bariatric Surgery, Medanta The Medicity, Haryana, India

Rashi Sharma

Department of Histopathology, Medanta The Medicity, Gurgaon, Haryana, India

Amanjeet Singh

Director and Head of Colorectal Surgery, Division of GI Surgery, GI Oncology, Minimal Access, and Bariatric Surgery, Medanta The Medicity, Haryana, India

Publication History

Received: July 23, 2020

Revised: August 11, 2020

Accepted: September 14, 2020

Published: October 13, 2020


Abstract


Background: Melanomas involving the gastrointestinal (GI) tract are usually metastatic from primary cutaneous sites. Primary GI melanoma is a rare entity and mostly presents with non-specific symptoms. The diagnosis in most of the cases is made retrospectively on the immunohistochemistry findings. Case Presentation: A 32-year-old male presented with massive upper GI bleeding necessitating a total gastrectomy, and to our surprise, on immunohistochemical staining, the diagnosis of primary gastric melanoma was confirmed. Conclusion: The possibilities of rare mesenchymal tumors of the stomach should be considered while treating such patients. A high index of suspicion in such atypical scenarios should warrant a positron emission tomography integrated with computed tomography to complete the staging workup. The natural course of the disease and its outcome is not known due to the paucity and rarity of this entity. Although the prognosis is dismal, it would help to prognosticate the patient and family before embarking onto a major surgical resection.

Keywords: Melanoma, primary gastric melanoma, melanin, S100, immunohistochemistry, green