Case Report
Volume: 4 | Issue: 9 | Published: Oct 14, 2020 | Pages: 285 - 287 | DOI: 10.24911/ejmcr/173-1567102492
An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration
Authors: Marta De Castro Martinez , Cristina Castillo Maza
Article Info
Authors
Marta De Castro Martinez
Internal Medicine Service, Hospital Universitario 12 de Octubre. Madrid, Spain
Cristina Castillo Maza
Internal Medicine Service, Hospital Universitario 12 de Octubre. Madrid, Spain.
Publication History
Received: August 29, 2019
Revised: April 06, 2020
Accepted: May 06, 2020
Published: October 14, 2020
Abstract
Background: The main use of Granulocyte colony stimulating factor (G-CSF) is stem cell mobilization in neutropenic patients and healthy donors as well as for engraftment. Most of their secondary effects are mild and temporary; however, there is a relation between spontaneous splenic rupture and G-CSF treatment. Case Presentation: We report a case of an 88-year old man, who presented with a spontaneous splenic rupture after use of G-CSF. Conclusion: Although it is an uncommon side effect, the mortality is very high, so clinicians should be aware of the importance about maintaining a high index of suspicion for this condition.
Keywords: Case report, spleen, hemoperitoneum, shock, neutropenia, green
