EJMCR |

Case Report

Volume: 4 | Issue: 9 | Published: Oct 06, 2020 | Pages: 280 - 284 | DOI: 10.24911/ejmcr/173-1554056047

Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant

Authors: Ashini Shah , Brinda S. Chandibhamar , Amisha Gami , Priti Trivedi

Article Info

Authors

Ashini Shah

Department of Oncopathology, Gujarat Cancer Research Institute, Civil Hospital, Ahmedabad, India

Brinda S. Chandibhamar

Department of Oncopathology, Gujarat Cancer Research Institute, Civil Hospital, Ahmedabad, India

Amisha Gami

Department of Oncopathology, Gujarat Cancer Research Institute, Civil Hospital, Ahmedabad, India

Priti Trivedi

Department of Oncopathology, Gujarat Cancer Research Institute, Civil Hospital, Ahmedabad, India

Publication History

Received: April 07, 2019

Revised: July 13, 2020

Accepted: September 03, 2020

Published: October 06, 2020

Abstract

Background: Intrahepatic cholangiocarcinoma (ICC) is arising from the intrahepatic bile ducts and accounts for 8%-10% of all malignant hepatic tumors. Case Presentation: We report the case of a 42-year-old woman having ICC with thyroid-like follicular pattern. The patient had 9-cm solitary liver mass showing morphological pattern resembling thyroid follicles. Immunohistochemistry was negative for thyroid markers. The patient had no evidence of a previous or concomitant thyroid tumor. This case can be added to the list of extrathyroidal primary tumor that morphologically resembles thyroid neoplasms. Only three such cases have been previously reported in the literature. Such a pattern is known to occur in primary kidney and breast tumor. Thyroid like pattern broadens the morphological spectrum of cholangiocarcinoma. Conclusion: Careful evaluation of this morphological rare variant of ICC is very essential to prevent misdiagnosis of metastatic thyroid follicular neoplasm.

Keywords: Cholangiocarcinoma, thyroid follicle-like pattern, thyroid transcription factor 1 (TTF-1), green

Pubmed Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi. Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant. EJMCR. 2020; 06 (October 2020): 280-284. doi:10.24911/ejmcr/173-1554056047

Web Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi. Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant. https://ejmcr.com/articles/1391 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1554056047

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi. Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant. EJMCR. (2020), [cited December 25, 2024]; 06 (October 2020): 280-284. doi:10.24911/ejmcr/173-1554056047

Harvard Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi (2020) Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant. EJMCR, 06 (October 2020): 280-284. doi:10.24911/ejmcr/173-1554056047

Chicago Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi. "Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant." 06 (2020), 280-284. doi:10.24911/ejmcr/173-1554056047

MLA (The Modern Language Association) Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi. "Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant." 06.October 2020 (2020), 280-284. Print. doi:10.24911/ejmcr/173-1554056047

APA (American Psychological Association) Style

Ashini Shah, Brinda S. Chandibhamar, Amisha Gami, Priti Trivedi (2020) Case report of intrahepatic cholangiocarcinoma showing thyroid like follicular pattern: a rare morphological variant. , 06 (October 2020), 280-284. doi:10.24911/ejmcr/173-1554056047