Case Report
Volume: 4 | Issue: 12 | Published: Dec 24, 2020 | Pages: 449 - 452 | DOI: 10.24911/ejmcr/173-1601973044
Pemphigus vulgaris: a rare auto-immune skin disease
Authors: Nikhil Chandra Hanumanth Rao Pet , Sindhuja Govula , Shweta Racherla , Kodipelly Ramana Raju
Article Info
Authors
Nikhil Chandra Hanumanth Rao Pet
Pharm D 5th year, Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, SVS Medical hospital, Mahabubnagar, Telangana, India
Sindhuja Govula
Pharm D 5th year, Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, SVS Medical hospital, Mahabubnagar, Telangana, India
Shweta Racherla
Pharm D 4th year, Department of Pharmacy Practice, Sri Venkateshwara College of Pharmacy, Apollo hospital, Hyderabad, Telangana, India
Kodipelly Ramana Raju
Pharm D 4th year, Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, SVS Medical hospital, Mahabubnagar, Telangana, India
Publication History
Received: October 06, 2020
Revised: October 25, 2020
Accepted: November 15, 2020
Published: December 24, 2020
Abstract
Background: Pemphigus vulgaris (PV) is a rare autoimmune chronic blistering skin disease of type II hypersensitivity reaction. Case Presentation: The authors present a case of a 42-year-old male with the chief complaint of crusted plaques on face, chest, and scalp for 3 months associated with itching. On investigation, direct immunofluorescence showed immunoglobulin G antibodies. The patient was prescribed antibiotics, anti-inflammatory agents etc., but they did not show any effect. So, the physicians opted for pulse therapy. Conclusion: PV is a rare chronic ulceration of the mucosa where crusted plaques and blisters are seen. This condition can be effectively resolved using glucocorticoids and immunosuppressant. If untreated, this may lead to the death of the patient.
Keywords: Case report, autoimmune, blistering, hypersensitivity, steroids, acanthosis, green
