Case Report
Volume: 5 | Issue: 2 | Published: Feb 10, 2021 | Pages: 31 - 34 | DOI: 10.24911/ejmcr/173-1576419538
Paraneoplastic factor XIII deficiency in a pregnant female with colon cancer: a case report
Authors: Claire Schumacher , Carole Bauer , Sigrid de Wilde , Patrick Paulus
Article Info
Authors
Claire Schumacher
University of Liège, Liège, Wallonia, Belgium
Carole Bauer
Centre Hospitalier du Luxembourg, Luxembourg City, Luxembourg
Sigrid de Wilde
Centre Hospitalier du Luxembourg, Luxembourg City, Luxembourg
Patrick Paulus
Centre Hospitalier du Luxembourg, Luxembourg City, Luxembourg
Publication History
Received: December 15, 2019
Revised: December 27, 2020
Accepted: January 02, 2021
Published: February 10, 2021
Abstract
Background: Factor XIII deficiency, which can be congenital or acquired, is a rare disorder. It can cause life-threatening bleeding. It cannot be diagnosed by usual hemostasis tests; only by specific screening tests. Case Presentation: We report the case of a young pregnant woman whom we discovered a paraneoplastic factor XIII deficiency with the underlying cause of colorectal cancer. Conclusion: A paraneoplastic context concerning hematologic malignancies as well as solid tumors must not be ignored. No other case of paraneoplastic factor XIII deficiency resulting from colorectal cancer is previously reported in the literature.
Keywords: Factor XIII, pregnancy, paraneoplastic syndrome, colorectal cancer, case report, green
