Case Report
Volume: 5 | Issue: 7 | Published: Jul 02, 2021 | Pages: 197 - 202 | DOI: 10.24911/ejmcr/173-1602581515
Total skin electron beam therapy in mycosis fungoides
Authors: Susana Sarandao , Angelo Paiva Oliveira , Isabel Oliveira
Article Info
Authors
Susana Sarandao
External Radiotherapy Department, Instituto Portugues de Oncologia Francisco Gentil do Porto, Porto, Portugal
Angelo Paiva Oliveira
External Radiotherapy Department, Instituto Portugues de Oncologia Francisco Gentil do Porto, Porto, Portugal
Isabel Oliveira
Onco-Haematology Department, Instituto Portugues de Oncologia Francisco Gentil do Porto, Porto, Portugal
Publication History
Received: October 13, 2020
Revised: March 03, 2021
Accepted: April 20, 2021
Published: July 02, 2021
Abstract
Background: Mycosis fungoides (MF) is a rare type of non-Hodgkins lymphoma of T cells that primarily affects the skin. Radiation therapy is a cornerstone of therapy for all stages. Case Presentation: A 76-year-old man diagnosed in 2010 with MF in the patch/plaque phase (stage IB T2 N0 M0 B0) was treated with topical corticosteroids and successive sessions of photochemotherapy (psoralen and ultraviolet A) and phototherapy (narrowband ultraviolet B) with relative control of the lesional condition for 9 years. Due to the absence of clinical response and progression of the lesions, it was proposed for the treatment with radiotherapy. The patient underwent total skin electron beam therapy (TSEBT) (6 MeV electron/30/1 Gy per day/4 days per week). The patient showed marked improvement of the lesional condition with minimal toxicity. Remains in follow-up, with good control of the disease to date. Conclusion: MF is a challenging disorder from all perspectives. TSEBT in patients with extensive patches or plaques has an excellent response rate and rapid palliation.
Keywords: T-cell lymphoma cutaneous, mycosis fungoides, skin neoplasms, radiotherapy, total skin electron beam therapy, case report, green
