Case Report
Volume: 6 | Issue: 5 | Published: Aug 09, 2022 | Pages: 79 - 83 | DOI: 10.24911/ejmcr/173-1632298824
Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report
Authors:
Nadia Sharif
, Sana Nasir
, Niaz Hussain Soomro
Article Info
Authors
Nadia Sharif
Assistant Professor, Ojha Institute of Chest Diseases, Department of Pulmonology, Dow University of Health Sciences, Karachi, Pakistan
Sana Nasir
Department of Pulmonology, Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, Pakistan
Niaz Hussain Soomro
Department of Pulmonology, Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, Pakistan.
Publication History
Received: September 22, 2021
Accepted: May 22, 2022
Published: August 09, 2022
Abstract
Background: Bipolaris species are dematiaceous fungi that originally are plant pathogens but have been reported to cause a wide spectrum of diseases in both immunocompromised and immunocompetent human hosts. Case Presentation: We report a case of a young immunocompetent man who presented with fever, dry cough, and malaise. He had unilateral pleural effusion with mediastinal mass. Histopathology of pleura and mediastinal mass revealed granulomatous inflammation with fungal pseudohyphae. Tissue cultures grew Bipolaris species. He is on itraconazole with significant clinical improvement. Conclusion: This clinical presentation of Bipolaris infection has not been previously described. In Pakistan, where tuberculosis leuritis is frequently encountered, this case highlights that other rare causes of granulomatous pleuritis can also present in a similar fashion.
Keywords: Case report, Pheohyphomycosis, granulomatous pleuritis, Bipolaris infection, green
