Case Report

Volume: 5 | Issue: 12 | Published: Dec 21, 2021 | Pages: 345 - 349 | DOI: 10.24911/ejmcr/173-1630476749

Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report


Authors: Nayyar Rubab , Muhammad Shahzad Afzal , Muhammad Shahbaz , Muhammad Babar Imran


Article Info

Authors

Nayyar Rubab

Department of Nuclear Medicine, PINUM Cancer Hospital, Faisalabad, Pakistan

Muhammad Shahzad Afzal

Department of Nuclear Medicine, PINUM Cancer Hospital, Faisalabad, Pakistan

Muhammad Shahbaz

Department of Medical Physics, PINUM Cancer Hospital, Faisalabad, Pakistan

Muhammad Babar Imran

Department of Nuclear Medicine, PINUM Cancer Hospital, Faisalabad, Pakistan

Publication History

Received: September 01, 2021

Revised: October 14, 2021

Accepted: October 14, 2021

Published: December 21, 2021


Abstract


Background: Papillary thyroid cancer (PTC) accounts for 90% of the thyroid malignancies with predominance in females. Distant metastasis is usually seen in lungs and bones. The treatment of metastatic papillary cancer thyroid is total/near total thyroidectomy followed by radioactive iodine (RAI) ablation. Lung metastasis shows a good response to RAI therapy. Case Presentation: We describe a case of a 22-year-old female, referred to the nuclear medicine department after surgery for RAI ablation. The patient was diagnosed case of PTC. The first dose of 100 mCi of RAI under steroid cover was given. The post-therapy scan showed bilateral pulmonary metastasis. However, follow-up I-131 whole-body imaging after 2 years showed no evidence of functioning thyroid tissue/metastasis. Conclusion: PTC with lung metastasis has a good prognosis and better survival in young patients treated with RAI. A single dose of RAI (I-131) may cure extensive lung metastasis.

Keywords: Papillary CA thyroid, Pulmonary metastasis, RAI ablation, Case report, green