Case Report

Volume: 5 | Issue: 12 | Published: Jan 02, 2022 | Pages: 334 - 336 | DOI: 10.24911/ejmcr/173-1621160240

Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report


Authors: Paul El Meouchy orcid logo , Noha Bejjani , Maroun Abou Nader , Roula Farah


Article Info

Authors

Paul El Meouchy

Department of Internal Medicine, University of Balamand, Beirut, Lebanon

orcid logo ORCID

Noha Bejjani

Department of Pathology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon

Maroun Abou Nader

Department of Spinal Surgery, Dr Sulaiman Al Habib Hospital, Al Rayan district, Riyadh, Saudi Arabia

Roula Farah

Department of Pediatrics, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon

Publication History

Received: May 16, 2021

Revised: October 12, 2021

Accepted: October 12, 2021

Published: January 02, 2022


Abstract


Background: Mature teratomas are common tumors in the pediatric population. They can arise in the central nervous system and often require surgical resection. They are classified as non-germinomatous germ cell tumors and their recurrence are extremely rare. Case Presentation: We are reporting the case of a 6-year-old boy who was diagnosed with mature pineal teratoma after he presented with signs of acute hydrocephalus. Histopathology did not reveal any other germ cell tumor component. He underwent a complete resection of the mass, with no adjuvant chemotherapy. Nine years post-operatively, magnetic resonance imaging results showed recurrence of the pineal tumor as a germinoma. Chemotherapy and radiotherapy resulted in significant shrinkage of the mass and resolution of the clinical symptoms. Conclusion: This case illustrates the possibility of the late recurrence of a germinoma after the complete removal of a mature intracranial teratoma. It also raises the issue of whether mature teratomas should be treated with adjuvant therapy after surgical resection to prevent their recurrence as another germ cell tumor.

Keywords: Germinoma, mature teratoma, germ cell tumor, pineal teratoma, case report, green