Case Report
Volume: 7 | Issue: 1 | Published: Dec 25, 2022 | Pages: 6 - 12 | DOI: 10.24911/ejmcr/173-1649603180
Atypical metastasis localization, buccal mucosa,in a patient with invasive lobular breast cancer: a case report
Authors:
Talar Ozler
, Rusen Cosar
, Dilek Nurlu
, Ebru Tastekin
, Sernaz Uzunoglu
, Tulin Yalta
, Yusuf Kavuzlu
, Serdar Solak
, Sule Parlar
, Bilge Avcı
, Zeynep Alas
, Mustafa Cem Uzal
Article Info
Authors
Talar Ozler
Radiation Oncology Department, Trakya University Faculty of Medicine, Edirne, Turkey
Dilek Nurlu
Department of Medical Oncology, Trakya University Faculty of Medicine, Edirne, Turkey
Ebru Tastekin
Department of Radiology, Trakya University Faculty of Medicine, Edirne, Turkey
Sernaz Uzunoglu
University of Strasbourg Faculty of Life Sciences, Strasbourg, France
Tulin Yalta
Department of Radiation Oncology, Istanbul Arel University Faculty of Medicine, Istanbul, Turkey.
Yusuf Kavuzlu
Radiation Oncology Department, Trakya University Faculty of Medicine, Edirne, Turkey
Serdar Solak
Department of Radiology, Trakya University Faculty of Medicine, Edirne, Turkey
Sule Parlar
Radiation Oncology Department, Trakya University Faculty of Medicine, Edirne, Turkey
Bilge Avcı
Department of Pathology, Trakya University Faculty of Medicine, Edirne, Turkey
Zeynep Alas
University of Strasbourg Faculty of Life Sciences, Strasbourg, France
Mustafa Cem Uzal
Department of Radiation Oncology, Istanbul Arel University Faculty of Medicine, Istanbul, Turkey
Publication History
Received: April 11, 2022
Revised: August 01, 2022
Accepted: August 01, 2022
Published: December 25, 2022
Abstract
Background: Buccal mucosa metastasis is rare in breast cancer patients. Case Presentation: A 50-year-old female breast cancer patient with invasive lobular carcinoma (ILC) in his eight years follow-up period presented with a swelling in the right eye. Head and neck MRI was showed soft tissue formation with dimensions of 59x31 mm was detected in the axial plane, extending from the level of the right infratemporal fossa to the right buccinator muscle and right maxillary sinus in front of the alveolar process. In the right periorbital region, there was a thickness increase of up to 1 cm in the thickest part of the globe, which was evident in the anterolateral. In addition, there was no bone destruction in the right infratemporal region in maxillofacial CT, and no additional organ metastasis was detected in PET-CT performed for systemic scanning. In the histopathological examination of the tissue, carcinoma infiltration was detected. Radiotherapy was applied to the right buccal and orbital region of the patient as 30 Gy in 12 fractions (2.5 Gy per fraction) with volumetric modulated arc therapy technique and then 15 Gy in 6 fractions (2.5 Gy per fraction) boost radiotherapy with the adaptive technique were applied. At the follow-up 2 months later, clinical response was observed in the patient, and significant regression of the lesion was observed in facial and orbital MRI. At the 15th month follow-up of the patient, clinical and radiological remission continues. All clinical complaints regressed. Conclusion: ILC is a subtype of breast cancer that is characterized by unusual metastasis. Therefore, during the follow-up of these patients, it is necessary to monitor both laboratory values and clinical complaints very carefully.
Keywords: Radiotherapy, lobular carcinoma, metastasis, breast cancer, buccal mucosa, green
