Case Report

Volume: 7 | Issue: 8 | Published: Jan 12, 2024 | Pages: 164 - 166 | DOI: 10.24911/ejmcr/173-1677945890

Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report


Authors: Arnab Chakraborty orcid logo , Shail Jalan , Diptendra Sarkar


Article Info

Authors

Arnab Chakraborty

Department of Surgical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, New Delhi, India

orcid logo ORCID

Shail Jalan

Resident, Department of Surgery, IPGME&R and SSKM Hospital, Kolkata

Diptendra Sarkar

Professor, Comprehensive Breast Clinic, Department of Surgery, IPGME&R and SSKM Hospital, Kolkata

Publication History

Received: March 04, 2023

Revised: June 17, 2023

Accepted: June 17, 2023

Published: January 12, 2024


Abstract


Background: Malignant peripheral nerve sheath tumor (MPNST) is a rare variety of soft 10-tissue sarcoma of ectomesenchymal origin. It represents approximately 10% of all soft tissue sarcomas. Though these tumors due to their Schwann cell origin may occur anywhere near a nerve trunk, breast is a rare site of its occurrence. This is a rare case of MPNST arising in the breast and not associated with neurofibromatosis type 1.
Case Presentation: A 22-year-old female presented with a large painless breast lump for 5 months, which was clinically suspected to be a Carcinoma. No confirmatory results were 18 obtained with fine needle aspiration biopsy , core biopsy, and magnetic resonance imaging. Wide local excision was done. Histopathology and immunohistochemistry confirmed MPNST. Furthermore, she underwent adjuvant radiation to her breast.
Conclusion: The unusual location and size of the tumor make our study noteworthy. Owing to the infrequent occurrence of the tumor, there are no definite guidelines for its management. We recommend wide local excision with postop radiotherapy as the optimum treatment for this condition.


Keywords: Malignant Peripheral Nerve Sheath tumor, soft tissue sarcoma, breast, immunohistochemistry, Wide local excision, green


Pubmed Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar. Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report. EJMCR. 2024; 12 (January 2024): 164-166. doi:10.24911/ejmcr/173-1677945890

Web Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar. Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report. https://ejmcr.com/articles/1206 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1677945890

AMA (American Medical Association) Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar. Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report. EJMCR. 2024; 12 (January 2024): 164-166. doi:10.24911/ejmcr/173-1677945890

Vancouver/ICMJE Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar. Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report. EJMCR. (2024), [cited December 25, 2024]; 12 (January 2024): 164-166. doi:10.24911/ejmcr/173-1677945890

Harvard Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar (2024) Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report. EJMCR, 12 (January 2024): 164-166. doi:10.24911/ejmcr/173-1677945890

Chicago Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar. "Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report." 12 (2024), 164-166. doi:10.24911/ejmcr/173-1677945890

MLA (The Modern Language Association) Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar. "Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report." 12.January 2024 (2024), 164-166. Print. doi:10.24911/ejmcr/173-1677945890

APA (American Psychological Association) Style

Arnab Chakraborty, Shail Jalan, Diptendra Sarkar (2024) Malignant Peripheral Nerve Sheath Tumour mimicking as breast cancer: a case report. , 12 (January 2024), 164-166. doi:10.24911/ejmcr/173-1677945890