Case Report
Volume: 6 | Issue: 8 | Published: Nov 28, 2022 | Pages: 147 - 151 | DOI: 10.24911/ejmcr/173-1663695748
Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases
Authors:
Stephanie Farrugia
, Michael J. Boffa
Article Info
Authors
Michael J. Boffa
Department of Dermatology and Venerology, Mater Dei Hospital, Msida, Malta.
Publication History
Received: September 20, 2022
Accepted:
Published: November 28, 2022
Abstract
Background: Sarcoidosis is a noncaseating granulomatous disease that affects multiple systems, including the skin. Treatment for cutaneous sarcoidosis is varied and mostly based on anecdotal knowledge from the literature. The commonest treatment for cutaneous sarcoidosis involves topical, intralesional, and/or systemic corticosteroids. Other treatments, including retinoids, have been trialed with varying response. Case presentation: A 71-year-old female had been diagnosed with cutaneous sarcoidosis when she was 59 years old. She was initially treated with corticosteroids, followed by methotrexate until the age of 68 years, at which point she was switched to acitretin due to failure of resolution on the previous treatment. The patient's condition improved dramatically within 8 months of treatment. Conclusion: A literature review identified eight other cases of cutaneous sarcoidosis treated with retinoids (isotretinoin in six cases and etretinate in two cases). Of these cases, only one responded unfavorably, whereas resolution was seen within 8 months in the other seven cases, similar to our case. This suggests that retinoids may be a potential treatment option for cutaneous sarcoidosis, possibly owing to their anti-inflammatory and immunomodulatory properties.
Keywords: Retinoids, acitretin, granuloma, recalcitrant cutaneous sarcoidosis, case report, green
Pubmed Style
Stephanie Farrugia, Michael J. Boffa. Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases. EJMCR. 2022; 28 (November 2022): 147-151. doi:10.24911/ejmcr/173-1663695748
Web Style
Stephanie Farrugia, Michael J. Boffa. Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases. https://ejmcr.com/articles/1103 [Access: December 04, 2024]. doi:10.24911/ejmcr/173-1663695748
AMA (American Medical Association) Style
Stephanie Farrugia, Michael J. Boffa. Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases. EJMCR. 2022; 28 (November 2022): 147-151. doi:10.24911/ejmcr/173-1663695748
Vancouver/ICMJE Style
Stephanie Farrugia, Michael J. Boffa. Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases. EJMCR. (2022), [cited December 04, 2024]; 28 (November 2022): 147-151. doi:10.24911/ejmcr/173-1663695748
Harvard Style
Stephanie Farrugia, Michael J. Boffa (2022) Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases. EJMCR, 28 (November 2022): 147-151. doi:10.24911/ejmcr/173-1663695748
Chicago Style
Stephanie Farrugia, Michael J. Boffa. "Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases." 28 (2022), 147-151. doi:10.24911/ejmcr/173-1663695748
MLA (The Modern Language Association) Style
Stephanie Farrugia, Michael J. Boffa. "Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases." 28.November 2022 (2022), 147-151. Print. doi:10.24911/ejmcr/173-1663695748
APA (American Psychological Association) Style
Stephanie Farrugia, Michael J. Boffa (2022) Cutaneous Sarcoidosis treated with Retinoids: A Case Report and Review of Nine Cases. , 28 (November 2022), 147-151. doi:10.24911/ejmcr/173-1663695748