Case Report

Volume: 5 | Issue: 3 | Published: Feb 28, 2021 | Pages: 98 - 101 | DOI: 10.24911/ejmcr/173-1605526618

Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report


Authors: Munaza Batool Rizvi orcid logo , Shivanand S Medar


Article Info

Authors

Munaza Batool Rizvi

Pediatric Emergency Medicine Fellow, Division of Pediatric Emergency Medicine, Albert Einstein College of Medicine, Children’s Hospital at Montefiore, Bronx NY

orcid logo ORCID

Shivanand S Medar

Attending Physician, Division of Pediatric Critical Care Medicine, Assistant Professor of Pediatrics, Albert Einstein College of Medicine, Children’s Hospital at Montefiore, Bronx NY.

Publication History

Received: November 16, 2020

Revised: January 04, 2021

Accepted: February 01, 2021

Published: February 28, 2021


Abstract


Background: Combined autoimmune neutropenia (AIN) and immune thrombocytopenia (ITP) is a rare disease that can present as extremely low neutrophil count and platelet count, respectively [1]. Case Presentation: We describe the first case, to the authors’ knowledge, of the novel SARS CoV-2 infection and combined AIN and ITP in a healthy 27-year-old male. Conclusion: Viruses have been known to trigger autoimmune diseases in people with genetic predisposition. We speculate that the patient’s selective IgM deficiency predisposed him to have autoimmune cytopenia, and SARS-COV-2 triggered him to acquire combined AIN and ITP. Our hypothesis is supported by a lack of evidence of malignancy, a normal morphology on the smear, and an immediate response to IVIG infusion with significant improvement in platelet and neutrophilic count.

Keywords: Coronavirus, COVID-19, IVIG, combined autoimmune neutropenia (AIN), green


Pubmed Style

Munaza Batool Rizvi, Shivanand S Medar. Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report. EJMCR. 2021; 28 (February 2021): 98-101. doi:10.24911/ejmcr/173-1605526618

Web Style

Munaza Batool Rizvi, Shivanand S Medar. Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report. https://ejmcr.com/articles/1350 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1605526618

AMA (American Medical Association) Style

Munaza Batool Rizvi, Shivanand S Medar. Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report. EJMCR. 2021; 28 (February 2021): 98-101. doi:10.24911/ejmcr/173-1605526618

Vancouver/ICMJE Style

Munaza Batool Rizvi, Shivanand S Medar. Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report. EJMCR. (2021), [cited December 25, 2024]; 28 (February 2021): 98-101. doi:10.24911/ejmcr/173-1605526618

Harvard Style

Munaza Batool Rizvi, Shivanand S Medar (2021) Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report. EJMCR, 28 (February 2021): 98-101. doi:10.24911/ejmcr/173-1605526618

Chicago Style

Munaza Batool Rizvi, Shivanand S Medar. "Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report." 28 (2021), 98-101. doi:10.24911/ejmcr/173-1605526618

MLA (The Modern Language Association) Style

Munaza Batool Rizvi, Shivanand S Medar. "Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report." 28.February 2021 (2021), 98-101. Print. doi:10.24911/ejmcr/173-1605526618

APA (American Psychological Association) Style

Munaza Batool Rizvi, Shivanand S Medar (2021) Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report. , 28 (February 2021), 98-101. doi:10.24911/ejmcr/173-1605526618