Case Report
Volume: 5 | Issue: 3 | Published: Feb 28, 2021 | Pages: 98 - 101 | DOI: 10.24911/ejmcr/173-1605526618
Novel coronavirus disease 2019 and combined autoimmune neutropenia and thrombocytopenia: a case report
Authors:
Munaza Batool Rizvi
, Shivanand S Medar
Article Info
Authors
Munaza Batool Rizvi
Pediatric Emergency Medicine Fellow, Division of Pediatric Emergency Medicine, Albert Einstein College of Medicine, Childrens Hospital at Montefiore, Bronx NY
Shivanand S Medar
Attending Physician, Division of Pediatric Critical Care Medicine, Assistant Professor of Pediatrics, Albert Einstein College of Medicine, Childrens Hospital at Montefiore, Bronx NY.
Publication History
Received: November 16, 2020
Revised: January 04, 2021
Accepted: February 01, 2021
Published: February 28, 2021
Abstract
Background: Combined autoimmune neutropenia (AIN) and immune thrombocytopenia (ITP) is a rare disease that can present as extremely low neutrophil count and platelet count, respectively [1]. Case Presentation: We describe the first case, to the authors knowledge, of the novel SARS CoV-2 infection and combined AIN and ITP in a healthy 27-year-old male. Conclusion: Viruses have been known to trigger autoimmune diseases in people with genetic predisposition. We speculate that the patients selective IgM deficiency predisposed him to have autoimmune cytopenia, and SARS-COV-2 triggered him to acquire combined AIN and ITP. Our hypothesis is supported by a lack of evidence of malignancy, a normal morphology on the smear, and an immediate response to IVIG infusion with significant improvement in platelet and neutrophilic count.
Keywords: Coronavirus, COVID-19, IVIG, combined autoimmune neutropenia (AIN), green
