Case Report

Volume: 4 | Issue: 7 | Published: Jul 25, 2020 | Pages: 235 - 239 | DOI: 10.24911/ejmcr/173-1588699898

Convulsions with propofol during drug-induced sleep endoscopy (DISE)


Authors: Fiorita Antonella , Di Cesare Tiziana , Galli Jacopo , Corina Luigi , Rizzotto Grazia , De Cosmo Germano , Paludetti Gaetano


Article Info

Authors

Fiorita Antonella

Department: “Scienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo”. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

Di Cesare Tiziana

Department: “Scienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo”. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

Galli Jacopo

Department: “Scienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo”. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

Corina Luigi

Department: “Scienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo”. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

Rizzotto Grazia

Department: “Scienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo”. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

De Cosmo Germano

Department: Scienze dell'emergenza, anestesiologiche e della rianimazione. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

Paludetti Gaetano

Department: “Scienze dell'invecchiamento, neurologiche, ortopediche e della testa-collo”. Fondazione Policlinico Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

Publication History

Received: May 05, 2020

Accepted: May 18, 2020

Published: July 25, 2020


Abstract


Background Drug-induced sleep endoscopy (DISE) is a useful method to evaluate multiobstructive sites simulating sleep with drugs; and propofol is the most widely used sedative for this purpose. Different adverse effects have been reported for propofol, including decrease in ventilatory drive and respiratory depression. Several clinical reports have also suggested a possible excitatory effect on the CNS. The supporting electroencephalographic (EEG) evidence is variable; in some cases, where the EEG has been monitored during the administration of propofol, epileptiform activity is not accompanied by motor manifestations, while in other cases, the EEG recordings after the events are reported as normal. Case presentation A 44-year-old male OSA patient, with negative neurological history, had three close episodes of generalized tonic-clonic seizures during DISE few minutes after sedation with increasing doses of propofol. Polygraphic intraoperative recording with EEG monitoring showed the evidence of epileptiform activity. Conclusion The complete polygraphic intraoperative recording during DISE, inclusive of brain electrical function monitoring, allowed us to record the proconvulsive effect of propofol – a rare but possible adverse event.

Keywords: DISE, OSAS, Sleep Endoscopy, propofol, convulsions, case report, green


Pubmed Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano. Convulsions with propofol during drug-induced sleep endoscopy (DISE). EJMCR. 2020; 25 (July 2020): 235-239. doi:10.24911/ejmcr/173-1588699898

Web Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano. Convulsions with propofol during drug-induced sleep endoscopy (DISE). https://ejmcr.com/articles/1410 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1588699898

AMA (American Medical Association) Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano. Convulsions with propofol during drug-induced sleep endoscopy (DISE). EJMCR. 2020; 25 (July 2020): 235-239. doi:10.24911/ejmcr/173-1588699898

Vancouver/ICMJE Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano. Convulsions with propofol during drug-induced sleep endoscopy (DISE). EJMCR. (2020), [cited December 25, 2024]; 25 (July 2020): 235-239. doi:10.24911/ejmcr/173-1588699898

Harvard Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano (2020) Convulsions with propofol during drug-induced sleep endoscopy (DISE). EJMCR, 25 (July 2020): 235-239. doi:10.24911/ejmcr/173-1588699898

Chicago Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano. "Convulsions with propofol during drug-induced sleep endoscopy (DISE)." 25 (2020), 235-239. doi:10.24911/ejmcr/173-1588699898

MLA (The Modern Language Association) Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano. "Convulsions with propofol during drug-induced sleep endoscopy (DISE)." 25.July 2020 (2020), 235-239. Print. doi:10.24911/ejmcr/173-1588699898

APA (American Psychological Association) Style

Fiorita Antonella, Di Cesare Tiziana, Galli Jacopo, Corina Luigi, Rizzotto Grazia, De Cosmo Germano, Paludetti Gaetano (2020) Convulsions with propofol during drug-induced sleep endoscopy (DISE). , 25 (July 2020), 235-239. doi:10.24911/ejmcr/173-1588699898