EJMCR |

Case Report

Volume: 4 | Issue: 6 | Published: Jun 25, 2020 | Pages: 186 - 189 | DOI: 10.24911/ejmcr/173-1563277232

An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis

Authors: Jayant Kumar Muduli , Meenakshi Mitra , Shweta Agarwal , Supriya Rashmi

Article Info

Authors

Jayant Kumar Muduli

Professor, Department of Pediatrics, IQ City Medical College and Narayana Multi-specialty Hospital, West Bengal, India

Meenakshi Mitra

Assistant Professor, Department of Pediatrics, IQ City Medical College and Narayana Multispecialty Hospital, West Bengal, India

Shweta Agarwal

Assistant Professor, Department of Pediatrics, IQ City Medical College and Narayana Multispecialty Hospital, West Bengal, India

Supriya Rashmi

Senior Resident, Department of Pediatrics, IQ City Medical College and Narayana Multi-specialty Hospital, West Bengal, India

Publication History

Received: July 30, 2019

Revised: April 10, 2020

Accepted: May 06, 2020

Published: June 25, 2020

Abstract

Background: Secondary hemophagocytic lymphohistiocytosis (HLH) is characterized by severe cytopenias due to uncontrolled hemophagocytosis. Other laboratory signs and clinical symptoms result from disordered immune regulation, and cytokine storm is well recognized. It is often a fatal complication of infections. It is not as uncommon as thought of previously. Case Presentation: We discuss a 7-year-old boy, born out of non-consanguineous marriage with acute hepatitis A infection, who developed HLH during treatment and was successfully managed with methyl prednisolone pulse therapy followed by oral prednisone therapy. Conclusion: Secondary HLH is a rare complication in a case of hepatitis A. A high index of suspicion at the early stage of HLH may produce a favorable outcome.

Keywords: Hemophagocytic lymphohistiocytosis, hepatitis A, injectable methyprednisolone, oral prednisolone, ferritin, triglycerides, green

Pubmed Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi. An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis. EJMCR. 2020; 25 (June 2020): 186-189. doi:10.24911/ejmcr/173-1563277232

Web Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi. An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis. https://ejmcr.com/articles/1414 [Access: December 04, 2024]. doi:10.24911/ejmcr/173-1563277232

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi. An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis. EJMCR. (2020), [cited December 04, 2024]; 25 (June 2020): 186-189. doi:10.24911/ejmcr/173-1563277232

Harvard Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi (2020) An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis. EJMCR, 25 (June 2020): 186-189. doi:10.24911/ejmcr/173-1563277232

Chicago Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi. "An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis." 25 (2020), 186-189. doi:10.24911/ejmcr/173-1563277232

MLA (The Modern Language Association) Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi. "An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis." 25.June 2020 (2020), 186-189. Print. doi:10.24911/ejmcr/173-1563277232

APA (American Psychological Association) Style

Jayant Kumar Muduli, Meenakshi Mitra, Shweta Agarwal, Supriya Rashmi (2020) An unusual complication of hepatitis A: secondary hemophagocytic lymphohistiocytosis. , 25 (June 2020), 186-189. doi:10.24911/ejmcr/173-1563277232