EJMCR |

Case Report

Volume: 4 | Issue: 2 | Published: Feb 29, 2020 | Pages: 65 - 69 | DOI: 10.24911/ejmcr/173-1560698497

POEMS syndrome: atypical presentation and therapeutic consideration

Authors: Ayman S. Abukamar , Majdi M. Abu-Awida , Saeed M. Abughazaleh , Ahmad R. Abdallah , Hamza M. Al-Zghool

Article Info

Authors

Ayman S. Abukamar

Hematology and Oncology Department, Royal Medical Services of Jordanian Army (RMS), Amman, Jordan

Majdi M. Abu-Awida

Neurology Department, Royal Medical Services of Jordanian Army (RMS), Amman, Jordan

Saeed M. Abughazaleh

Student at Medical School, Hashemite University, Jerash, Jordan

Ahmad R. Abdallah

Internship in University of Jordan Hospital, Amman, Jordan

Hamza M. Al-Zghool

Student at Medical School, Hashemite University, Jerash, Jordan

Publication History

Received: June 16, 2019

Revised: February 05, 2020

Accepted: February 08, 2020

Published: February 29, 2020

Abstract

Background: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare plasma cell dyscrasia, which could be presented as treatment-resistant polyneuropathy before the emergence of other systemic complications. Case Presentation: A 43-year-old male patient presented with progressive lower limb weakness and difficulty in walking, in addition to erectile dysfunction. After the diagnosis of POEMS syndrome, the patient was treated according to the standardized chemotherapeutic regimen for multiple myeloma that includes lenalidomide, without considering the increased risk of thromboembolic complications given that the patient had decreased ambulation due to his polyneuropathy and polycythemia. This warrants a better treatment regimen for these patients to eliminate any possible episode of thromboembolic complications, which might become fatal in the future. Conclusion: Although rare, it was recommended that deep vein thrombosis risk and its link to the proper treatment plan in patients with POEMS syndrome should be studied further.

Keywords: Case report, POEMS, polyneuropathy, thromboembolic, polycythemia, lenalidomide, green

Pubmed Style

Ayman S. Abukamar, Majdi M. Abu-Awida, Saeed M. Abughazaleh, Ahmad R. Abdallah, Hamza M. Al-Zghool. POEMS syndrome: atypical presentation and therapeutic consideration. EJMCR. 2020; 29 (February 2020): 65-69. doi:10.24911/ejmcr/173-1560698497

Web Style

Ayman S. Abukamar, Majdi M. Abu-Awida, Saeed M. Abughazaleh, Ahmad R. Abdallah, Hamza M. Al-Zghool. POEMS syndrome: atypical presentation and therapeutic consideration. https://ejmcr.com/articles/1455 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1560698497

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Ayman S. Abukamar, Majdi M. Abu-Awida, Saeed M. Abughazaleh, Ahmad R. Abdallah, Hamza M. Al-Zghool. POEMS syndrome: atypical presentation and therapeutic consideration. EJMCR. (2020), [cited December 25, 2024]; 29 (February 2020): 65-69. doi:10.24911/ejmcr/173-1560698497

Harvard Style

Ayman S. Abukamar, Majdi M. Abu-Awida, Saeed M. Abughazaleh, Ahmad R. Abdallah, Hamza M. Al-Zghool (2020) POEMS syndrome: atypical presentation and therapeutic consideration. EJMCR, 29 (February 2020): 65-69. doi:10.24911/ejmcr/173-1560698497

Chicago Style

Ayman S. Abukamar, Majdi M. Abu-Awida, Saeed M. Abughazaleh, Ahmad R. Abdallah, Hamza M. Al-Zghool. "POEMS syndrome: atypical presentation and therapeutic consideration." 29 (2020), 65-69. doi:10.24911/ejmcr/173-1560698497

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Ayman S. Abukamar, Majdi M. Abu-Awida, Saeed M. Abughazaleh, Ahmad R. Abdallah, Hamza M. Al-Zghool (2020) POEMS syndrome: atypical presentation and therapeutic consideration. , 29 (February 2020), 65-69. doi:10.24911/ejmcr/173-1560698497