EJMCR |

Case Report

Volume: 3 | Issue: 2 | Published: Jan 01, 1970 | Pages: 87 - 90 | DOI: 10.24911/ejmcr/173-1553374788

Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report

Authors: Asim Hassan , Bilal Jaja , Motasim Elamin , Saud Al Sifri

Article Info

Authors

Asim Hassan

Department of Diabetes and Endocrinology, Armed Forces Hospital AlHada, Taif, Saudi Arabia

Bilal Jaja

Department of Diabetes and Endocrinology, Armed Forces Hospital AlHada, Taif, Saudi Arabia

Motasim Elamin

Department of Diabetes and Endocrinology, Armed Forces Hospital AlHada, Taif, Saudi Arabia

Saud Al Sifri

Department of Diabetes and Endocrinology, Armed Forces Hospital AlHada, Taif, Saudi Arabia

Publication History

Received: March 23, 2019

Accepted: April 07, 2019

Published: January 01, 1970

Abstract

Background: With the introduction of recombinant formulations insulin allergy is rare, occurring in less than 1% of patients treated with insulin. However, it is a serious situation requiring immediate attention, both due to the hypersensitivity reaction and severe life threatening glucose disequilibrium. Case presentation: A case of a 68-year-old male known diabetic for 35 years noticed some generalized itching, accompanied with maculopapular, mixed vasculitic and bullous lesions. Humalog Mix50/50 was stopped and patient was started on different combinations but to no avail. Before insulin desensitization a trial of degludec was given. Fortunately, the patient tolerated degludec and vildagliptin, and sugars came under control. Conclusion: This combination of multi-hexamer-forming ultra-long-acting insulin plus a DPP4 inhibitor vildagliptin could be an effective combination in controlling blood sugars in patients who have severe allergy to multiple drugs including oral hypoglycemic agents and various insulin preparations.

Keywords: Insulin, allergy, Combination therapy, degludec, vildagliptin, case report, green

Pubmed Style

Asim Hassan, Bilal Jaja, Motasim Elamin, Saud Al Sifri. Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report. EJMCR. 1970; 01 (January 1970): 87-90. doi:10.24911/ejmcr/173-1553374788

Web Style

Asim Hassan, Bilal Jaja, Motasim Elamin, Saud Al Sifri. Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report. https://ejmcr.com/articles/1492 [Access: November 23, 2024]. doi:10.24911/ejmcr/173-1553374788

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Asim Hassan, Bilal Jaja, Motasim Elamin, Saud Al Sifri. Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report. EJMCR. (1970), [cited November 23, 2024]; 01 (January 1970): 87-90. doi:10.24911/ejmcr/173-1553374788

Harvard Style

Asim Hassan, Bilal Jaja, Motasim Elamin, Saud Al Sifri (1970) Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report. EJMCR, 01 (January 1970): 87-90. doi:10.24911/ejmcr/173-1553374788

Chicago Style

Asim Hassan, Bilal Jaja, Motasim Elamin, Saud Al Sifri. "Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report." 01 (1970), 87-90. doi:10.24911/ejmcr/173-1553374788

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Asim Hassan, Bilal Jaja, Motasim Elamin, Saud Al Sifri (1970) Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report. , 01 (January 1970), 87-90. doi:10.24911/ejmcr/173-1553374788