Authors: Ariba Shahid Tanveer , Nawal Navabjan , Ammar Shahid Tanweer , Mai Deraz , Luay Abdalwahab , Majd Hani Shaheen

Abstract

Background: Fixed drug eruption (FDE) is a recurrent cutaneous adverse drug reaction, with paracetamol-induced cases being rare and ocular involvement even more uncommon.

Case Presentation: We report a 6-year-old male who developed an isolated FDE of the right upper eyelid following paracetamol administration, presenting with erythema, edema, and subsequent hyperpigmentation. This rare presentation, with no systemic involvement, was diagnosed clinically, and management focused on strict avoidance of the offending drug. The patient recovered completely with residual hyperpigmentation after supportive management.

Conclusion: Given the limited reports of eyelid involvement in FDE, this case underscores the need for clinical awareness of its atypical manifestations to ensure timely diagnosis and appropriate management.

Keywords: Paracetamol, FDE, Allergy, Hypersensitivity, Eye