Case Report

Volume: 8 | Issue: 3 | Published: Apr 13, 2024 | Pages: 44 - 46 | DOI: 10.24911/ejmcr.173-1685921237

A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia


Authors: Husam Farraj , Kamelah Abushalha , Husam Bader , Mitchel F. Peabody , Claudia Kroker-Bode


Article Info

Authors

Husam Farraj

Department of Internal Medicine, Tallahassee Memorial Healthcare, Florida State University School of Medicine, Tallahassee, Florida, USA

Kamelah Abushalha

Department of Internal Medicine, MetroWest Medical Center, Tufts University School of Medicine, Framingham, Massachusetts, USA

Husam Bader

Department of Internal Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA

Mitchel F. Peabody

Department of Hemato-Oncology, Tallahassee Memorial Healthcare, Florida State University School of Medicine, Tallahassee, Florida, USA

Claudia Kroker-Bode

Department of Internal Medicine, Tallahassee Memorial Healthcare, Florida State University School of Medicine, Tallahassee, Florida, USA.

Publication History

Received: June 04, 2023

Accepted: November 28, 2023

Published: April 13, 2024


Abstract


Background: Anti-Ma2 antibody associated paraneoplastic syndrome (PNS) usually presents as limbic encephalitis in the context of testicular tumors. We report a rare case of anti-Ma2 positive PNS with deviation from the classic scenario, thus expanding the phenotype of anti-ma2 associated PNS. Case presentation: This is a 53-year-old male who presented with what was later diagnosed as anti-Ma2 antibody positive cerebellar ataxia. Further workup revealed retroperitoneal lymphadenopathy which, using biopsy, was identified as metastatic clear cell renal cell carcinoma (RCC). However, imaging did not reveal a primary renal lesion. Conclusion: Physicians should be aware of non-classic presentations of paraneoplastic syndromes, especially given that they commonly precede and point towards an underlying, many times undiagnosed, malignancy.

Keywords: Para-neoplastic Syndrome, Renal-cell Carcinoma, Cerebellar Ataxia, Tumor Regression, Case Report, green


Pubmed Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode. A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia. EJMCR. 2024; 13 (April 2024): 44-46. doi:10.24911/ejmcr.173-1685921237

Web Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode. A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia. https://ejmcr.com/articles/1252 [Access: December 25, 2024]. doi:10.24911/ejmcr.173-1685921237

AMA (American Medical Association) Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode. A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia. EJMCR. 2024; 13 (April 2024): 44-46. doi:10.24911/ejmcr.173-1685921237

Vancouver/ICMJE Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode. A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia. EJMCR. (2024), [cited December 25, 2024]; 13 (April 2024): 44-46. doi:10.24911/ejmcr.173-1685921237

Harvard Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode (2024) A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia. EJMCR, 13 (April 2024): 44-46. doi:10.24911/ejmcr.173-1685921237

Chicago Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode. "A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia." 13 (2024), 44-46. doi:10.24911/ejmcr.173-1685921237

MLA (The Modern Language Association) Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode. "A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia." 13.April 2024 (2024), 44-46. Print. doi:10.24911/ejmcr.173-1685921237

APA (American Psychological Association) Style

Husam Farraj, Kamelah Abushalha, Husam Bader, Mitchel F. Peabody, Claudia Kroker-Bode (2024) A malignancy phantom: a rare clinical case report of metastatic renal cell carcinoma with no evidence of a primary lesion presenting as cerebellar ataxia. , 13 (April 2024), 44-46. doi:10.24911/ejmcr.173-1685921237