A case report on pancreatic plasmacytoma presenting as obstructive jaundice
Authors:
Background: Extramedullary solitary plasmacytomas (EMD) are an uncommon manifestation of plasma cell disorders. The median survival rate is less than 6 months. EMD rarely involves the digestive tract, the liver is the most common site with only a 2.3% incidence rate for pancreatic involvement. Case Presentation: We report a case of a patient with a history of multiple myeloma who presented with painless obstructive jaundice and EUS findings of hypoechoic, solid irregular mass in the pancreatic head with surrounding peripancreatic lymphadenopathy. Fine needle aspirate (FNA) confirmed malignant infiltration of plasma cell neoplasm. The patient rapidly deteriorated and succumbed to his illness within 6 weeks of diagnosis. Conclusion: Extramedullary plasmacytomas (EMD) involving the pancreas are uncommon and associated with a poor prognosis. Our case highlights the importance of considering extramedullary plasmacytoma when a patient with MM presents with a pancreatic mass, particularly one showing a rapid interval growth. This rate of growth is not seen with primary pancreatic parenchymal diseases such as cancer, cysts, and so on. This case highlights the importance of considering rare differentials while evaluating patients with pancreatic mass.
Keywords: Case report, extramedullary plasmacytoma, pancreatic plasmacytoma, multiple myeloma, pancreatic mass.
Authors
Asiya Tafader
Division of Gastroenterology, Central Virginia VA Health Care System, Richmond, VA Division of Gastroenterology, Central Virginia VA Health Care System, Richmond, VA
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Mahum Nadeem
Division of Gastroenterology, Central Virginia VA Health Care System, Richmond, VA Division of Gastroenterology, Virginia Commonwealth University, Richmond, VA
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Joseph Spataro
Division of Gastroenterology, Central Virginia VA Health Care System, Richmond, VA Division of Gastroenterology, Virginia Commonwealth University, Richmond, VA.
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Correspondence to:
Mahum Nadeem, Division of Gastroenterology, Central Virginia VA Health Care System, Virginia, USA mahum.nadeem.md@gmail.com
Publication history:
Received 19 Jul 2023
Accepted 27 Apr 2024
Published online 21 Jul 2024
Tafader A, Nadeem M, Spataro J. A case report on pancreatic plasmacytoma presenting as obstructive jaundice. EJMCR. Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043
Tafader A, Nadeem M, Spataro J. A case report on pancreatic plasmacytoma presenting as obstructive jaundice. https://www.ejmcr.com/?mno=161737 [Access: September 01, 2024]. doi:
10.24911/ejmcr.173-1689784043
Tafader A, Nadeem M, Spataro J. A case report on pancreatic plasmacytoma presenting as obstructive jaundice. EJMCR. Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043
Tafader A, Nadeem M, Spataro J. A case report on pancreatic plasmacytoma presenting as obstructive jaundice. EJMCR, [cited September 01, 2024]; Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043
Tafader, A., Nadeem, . M. & Spataro, . J. (2024) A case report on pancreatic plasmacytoma presenting as obstructive jaundice. EJMCR, Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043
Tafader, Asiya, Mahum Nadeem, and Joseph Spataro. 2024. A case report on pancreatic plasmacytoma presenting as obstructive jaundice. European Journal of Medical Case Reports, Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043
Tafader, Asiya, Mahum Nadeem, and Joseph Spataro. "A case report on pancreatic plasmacytoma presenting as obstructive jaundice." European Journal of Medical Case Reports Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043
Tafader, Asiya, Mahum Nadeem, and Joseph Spataro. "A case report on pancreatic plasmacytoma presenting as obstructive jaundice." European Journal of Medical Case Reports Online First: 21 Jul, 2024. Web. 01 Sep 2024 doi:
10.24911/ejmcr.173-1689784043
Tafader, A., Nadeem, . M. & Spataro, . J. (2024) A case report on pancreatic plasmacytoma presenting as obstructive jaundice. European Journal of Medical Case Reports, Online First: 21 Jul, 2024. doi:
10.24911/ejmcr.173-1689784043