Neuroendocrine tumor in a longstanding tailgut cyst: a case report
Authors: Mirella Pace, Raduan Ahmed Franca, Pasquale Cretella, Maria Michela Di Nuzzo, Roberto Peltrini, Michele D ambra, Maria Laura Del Basso De Caro, Maria Rosaria D Armiento
Background: Retrocecal hamartomas are rare cystic lesions due to the persistence of the tailgut. Sometimes the epithelial or mesenchymal components of the cyst wall undergo neoplastic transformation, and, within them, carcinomas and sarcomas can develop. Case Presentation: We present the case of a multicystic lesion, discovered in a patient with perineal pain, which the imaging investigations have localized in the retrocecal space. The histological evaluation performed on his excisional biopsy demonstrates a retrocecal hamartoma harboring a neuroendocrine neoplasm. Conclusion: Tailgut cysts (TGC) are quite rare, only sometimes symptomatic, and infrequently, they also undergo a malignant transformation; in particular, the literature reviews report a higher frequency of adenocarcinomas. The differential diagnosis between lesions with different prognoses and pathogenesis that can develop in the retrocecal space requires a histological examination, which in some cases, becomes essential if we consider the potential for metastatic and local recurrence of any malignant neoplasm that arose in this site.
Keywords: Neuroendocrine tumor, retrorectal hamartoma, tail-gut.
Authors
Correspondence to:
Mirella Pace, Department of Biomorfological and Functional Sciences, University of Naples Federico II, Naples, Italy pacemirella@virgilio.it
Publication history:
Received 24 Apr 2022
Revised 15 Oct 2022
Accepted 17 Oct 2022
Published online 21 Nov 2022
Published in print 21 Nov 2022
Pace M, Franca RA, Cretella P, Nuzzo MMD, Peltrini R, ambra MD, , Armiento MRD. Neuroendocrine tumor in a longstanding tailgut cyst: a case report. EJMCR. 2022; 6(7): 119-122. doi:
10.24911/ejmcr/173-1650278347
Pace M, Franca RA, Cretella P, Nuzzo MMD, Peltrini R, ambra MD, , Armiento MRD. Neuroendocrine tumor in a longstanding tailgut cyst: a case report. https://www.ejmcr.com/?mno=19564 [Access: April 26, 2024]. doi:
10.24911/ejmcr/173-1650278347
Pace M, Franca RA, Cretella P, Nuzzo MMD, Peltrini R, ambra MD, , Armiento MRD. Neuroendocrine tumor in a longstanding tailgut cyst: a case report. EJMCR. 2022; 6(7): 119-122. doi:
10.24911/ejmcr/173-1650278347
Pace M, Franca RA, Cretella P, Nuzzo MMD, Peltrini R, ambra MD, , Armiento MRD. Neuroendocrine tumor in a longstanding tailgut cyst: a case report. EJMCR. (2022), [cited April 26, 2024]; 6(7): 119-122. doi:
10.24911/ejmcr/173-1650278347
Pace, M., Franca, . R. A., Cretella, . P., Nuzzo, . M. M. D., Peltrini, . R., ambra, . M. D., & Armiento, . M. R. D. (2022) Neuroendocrine tumor in a longstanding tailgut cyst: a case report. EJMCR, 6 (7), 119-122. doi:
10.24911/ejmcr/173-1650278347
Pace, Mirella, Raduan Ahmed Franca, Pasquale Cretella, Maria Michela Di Nuzzo, Roberto Peltrini, Michele D ambra, Maria Laura Del Basso De Caro, and Maria Rosaria D Armiento. 2022. Neuroendocrine tumor in a longstanding tailgut cyst: a case report. European Journal of Medical Case Reports, 6 (7), 119-122. doi:
10.24911/ejmcr/173-1650278347
Pace, Mirella, Raduan Ahmed Franca, Pasquale Cretella, Maria Michela Di Nuzzo, Roberto Peltrini, Michele D ambra, Maria Laura Del Basso De Caro, and Maria Rosaria D Armiento. "Neuroendocrine tumor in a longstanding tailgut cyst: a case report." European Journal of Medical Case Reports 6 (2022), 119-122. doi:
10.24911/ejmcr/173-1650278347
Pace, Mirella, Raduan Ahmed Franca, Pasquale Cretella, Maria Michela Di Nuzzo, Roberto Peltrini, Michele D ambra, Maria Laura Del Basso De Caro, and Maria Rosaria D Armiento. "Neuroendocrine tumor in a longstanding tailgut cyst: a case report." European Journal of Medical Case Reports 6.7 (2022), 119-122. Print. doi:
10.24911/ejmcr/173-1650278347
Pace, M., Franca, . R. A., Cretella, . P., Nuzzo, . M. M. D., Peltrini, . R., ambra, . M. D., & Armiento, . M. R. D. (2022) Neuroendocrine tumor in a longstanding tailgut cyst: a case report. European Journal of Medical Case Reports, 6 (7), 119-122. doi:
10.24911/ejmcr/173-1650278347