Case Report

Volume: 4 | Issue: 3 | Published: Mar 22, 2020 | Pages: 100 - 102 | DOI: 10.24911/ejmcr/173-1571237973

Intravascular hemolytic anemia and renal failure caused by myxoma


Authors: Elsa Soares , Patricia Valerio , Catarina Abrantes , Teresa Furtado , Ana Azevedo , Ana Farinha , Jose Assuncao


Article Info

Authors

Elsa Soares

Nephrology Department, Centro Hospitalar de Setubal, Portugal

Patricia Valerio

Nephrology Department, Centro Hospitalar de Setubal, Portugal

Catarina Abrantes

Nephrology Department, Centro Hospitalar de Setubal, Portugal

Teresa Furtado

Nephrology Department, Centro Hospitalar de Setubal, Portugal

Ana Azevedo

Nephrology Department, Hospital vila Franca de Xira, Portugal

Ana Farinha

Nephrology Department, Centro Hospitalar de Setubal, Portugal

Jose Assuncao

Nephrology Department, Centro Hospitalar de Setubal, Portugal

Publication History

Received: October 24, 2019

Accepted: March 07, 2020

Published: March 22, 2020


Abstract


Background: Cardiac myxoma is the most frequent “benign” tumor of the heart and presents an important diagnostic challenge. Case presentation: A 51-year-old woman was admitted at the hospital for anorexia, fatigue, nausea, and vomiting for the last 10 days. Laboratory results showed hemoglobin 5.26 g/dl, platelets 83× 10^9 μl, Lactate Dehydrogenase (LDH) 348 U/l, bilirubin 2.0 mg/dl, haptoglobin 100 mg/dl, negative Coombs test, blood smear with schistocytes and urea 327 mg/dl, creatinine 8.56 mg/dl. Non-autoimmune hemolytic anemia and acute kidney injury was assumed. After seven plasma exchange treatments, she went into acute pulmonary edema. Body tomography was performed, and revealed a mass in the left atrium. She underwent atriotomy and after surgery hemoglobin values stabilized but kidney function did not improve, and she became dialysis dependent. Conclusion: Myxomas can mimic other diseases which may delay diagnosis and compromise prognosis. In this particular case, the myxoma manifested with intravascular hemolytic anemia. This is an, especially, interesting case because a myxoma caused kidney failure without recovery.

Keywords: Cardiac tumor, myxoma, embolization, renal failure, hemolytic anemia, green