Case Report
Volume: 5 | Issue: 1 | Published: Jan 29, 2021 | Pages: 1 - 3 | DOI: 10.24911/ejmcr/173-1560272435
A case of vitamin B12 deficiency with some unusual features
Authors: Teresa Melo , Liliana Ribeiro dos Santos , Patricia Martins , Ana Paula Vilas
Article Info
Authors
Teresa Melo
Centro Hospitalar e Universitario Lisboa Norte, Lisboa, Portugal
Liliana Ribeiro dos Santos
Centro Hospitalar e Universitario Lisboa Norte, Lisboa, Portugal
Patricia Martins
Division of Medicine, University College of London, London, United Kingdom
Ana Paula Vilas
Centro Hospitalar e Universitario Lisboa Norte, Lisboa, Portugal
Publication History
Received: June 11, 2019
Revised: September 19, 2020
Accepted: September 19, 2020
Published: January 29, 2021
Abstract
Background: Vitamin B12 (VB12) deficiency is a pleomorphic disease with a wide range of manifestations. Its major cause is pernicious anemia, an autoantibody-mediated disease that results in low levels of intrinsic factor [1,2]. Case Presentation: We present a case report of a middle-aged man with severe megaloblastic anemia due to VB12 deficiency in relation to an unsuspected Crohns disease with exclusive ileum involvement. He also had some unusual neurological manifestations of this vitamins deficiency, such as hypersudoresis. Unlike most cases, the anemia was not hypoproliferative and hemolysis existed. Conclusion: This case reports some unusual aspects of VB12 deficiency and reminds us that ileum disease should be considered in patients with a negative autoimmune profile.
Keywords: Crohns disease, vitamin B12 deficiency, case report, weight loss, night sweats, anemia, green
