Case Report

Volume: 7 | Issue: 4 | Published: Mar 24, 2023 | Pages: 75 - 78 | DOI: 10.24911/ejmcr/173-1652790679

Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient


Authors: Ugur Aferin , Berin Selcuk , Cansu Turker , Ovgu Aydin Ulgen , Hamdi Ozkara


Article Info

Authors

Ugur Aferin

T.C. Demiroglu Science University, Department of Urology, Istanbul, Turkey

Berin Selcuk

Igdır State Hospital, Igdir, Turkey

Cansu Turker

Harakani Public Hospital, Kars, Turkey

Ovgu Aydin Ulgen

Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Pathology, Istanbul, Turkey

Hamdi Ozkara

Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Pathology, Istanbul, Turkey.

Publication History

Received: May 17, 2022

Accepted:

Published: March 24, 2023


Abstract


Background: Kaposi's sarcoma (KS) is a multifocal, angioproliferative malignant lesion originating from lymphatic endothelial cells. KS limited to the penis is extremely rare in human immunodeficiency virus (HIV) sero-negative patients. In this study, we aimed to present a case of isolated primary penile KS unrelated to HIV. Case Presentation: A 65-year-old man, with no risk factors for KS, presented with reddish nodules on penis. Biopsy was recommended to the patient for definitive diagnosis. Histopathological examination revealed that the diagnosis was classical type KS. No distant metastases were detected. No recurrence or disease progression was detected during the 4-year follow-up. Conclusion: Isolated primary penile KS is extremely rare in HIV sero-negative patients, but it should be kept in mind in the differential diagnosis of pigmented and nodular lesions in the penis. Excision of lesions with negative surgical margins has a high success and very low complication rate, as in our case.

Keywords: Kaposi sarcoma, penile nodule, HHV-8, penile lesion, HIV, green