Case Series

Volume: 7 | Issue: 3 | Published: Feb 16, 2023 | Pages: 70 - 74 | DOI: 10.24911/ejmcr/173-1668794112

Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series


Authors: Marcus Allen Healey , Nikki Duong , Kunal Patel , Brian Strife , Richard K. Sterling


Article Info

Authors

Marcus Allen Healey

Department of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

Nikki Duong

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

Kunal Patel

Division of Interventional Radiology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

Brian Strife

Division of Interventional Radiology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

Richard K. Sterling

Department of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.

Publication History

Received: November 18, 2022

Accepted:

Published: February 16, 2023


Abstract


Background: Transjugular intrahepatic portosystemic shunt (TIPS) is a therapeutic intervention for refractory ascites and variceal bleeding. However, the development of hepatic encephalopathy (HE) is a known complication. TIPS diameter can be reduced to decrease further HE episodes when refractory to pharmacotherapy. However, TIPS reduction for refractory hepatic encephalopathy (rHE) is poorly described. This case series identifies various characteristics and outcomes among this unique patient cohort. Case Presentation: In this cohort of 8 patients, 63% were male, 75% were Caucasian, and 38% had alcohol-associated cirrhosis. Following TIPS reduction, the number of HE-related admissions (mean, median) decreased from 2.1 and 2 to 1.6 and 0.5 while the number of non-HE admissions following TIPS reduction increased from 0.6 and 0 to 1 and 0.5. Conclusion: TIPS reduction reduced the number of hospitalizations for rHE but the total number of hospitalizations for all causes increased, demonstrating the high resource utilization for those with rHE following TIPS. Therefore, careful selection for initial TIPS placement remains a priority.

Keywords: Transjugular intrahepatic portosystemic shunt (TIPS), refractory ascites (RA), variceal bleed (VB), refractory hepatic encephalopathy (rHE), case report, green


Pubmed Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling. Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series. EJMCR. 2023; 16 (February 2023): 70-74. doi:10.24911/ejmcr/173-1668794112

Web Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling. Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series. https://ejmcr.com/articles/1072 [Access: December 04, 2024]. doi:10.24911/ejmcr/173-1668794112

AMA (American Medical Association) Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling. Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series. EJMCR. 2023; 16 (February 2023): 70-74. doi:10.24911/ejmcr/173-1668794112

Vancouver/ICMJE Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling. Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series. EJMCR. (2023), [cited December 04, 2024]; 16 (February 2023): 70-74. doi:10.24911/ejmcr/173-1668794112

Harvard Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling (2023) Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series. EJMCR, 16 (February 2023): 70-74. doi:10.24911/ejmcr/173-1668794112

Chicago Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling. "Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series." 16 (2023), 70-74. doi:10.24911/ejmcr/173-1668794112

MLA (The Modern Language Association) Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling. "Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series." 16.February 2023 (2023), 70-74. Print. doi:10.24911/ejmcr/173-1668794112

APA (American Psychological Association) Style

Marcus Allen Healey, Nikki Duong, Kunal Patel, Brian Strife, Richard K. Sterling (2023) Transjugular intrahepatic portosystemic shunt reduction for refractory hepatic encephalopathy: a case series. , 16 (February 2023), 70-74. doi:10.24911/ejmcr/173-1668794112