Case Report

Volume: 6 | Issue: 9 | Published: Dec 22, 2022 | Pages: 169 - 172 | DOI: 10.24911/ejmcr/173-1660205558

Case report of an unusual manifestation of anti-GBM disease


Authors: John Swayne , Ritienne Debono , Maria Bonello


Article Info

Authors

John Swayne

Department of Medicine, Division of Nephrology, Mater Dei Hospital, San Gwann, Malta

Ritienne Debono

Department of Medicine, Division of Nephrology, Mater Dei Hospital, San Gwann, Malta

Maria Bonello

Department of Neurology, Mater Dei Hospital, San Gwann, Malta.

Publication History

Received: August 27, 2022

Revised: November 28, 2022

Accepted: November 28, 2022

Published: December 22, 2022


Abstract


Background: Anti-GBM disease is a small vessel vasculitis that occurs when circulating antibodies against the glomerular basement membrane develop. It is a relatively rare disease, occurring in less than two cases per million population. The usual presentation is with renal or lung manifestations or with a combination of both. Case Presentation: Our case reports a patient who presented with end-stage renal disease secondary to anti-GBM disease, with no pulmonary manifestations, who later presented with a syndrome suggesting cerebral vasculitis, that responded to immunosuppressive treatment. Conclusion: Cerebral involvement in anti-GBM disease is very rare and to our knowledge, only a few cases have been so far reported.

Keywords: Anti-GBM disease, cerebral vasculitis, immunosuppression, small vessel vasculitis, green


Pubmed Style

John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. EJMCR. 2022; 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558

Web Style

John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. https://ejmcr.com/articles/1108 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1660205558

AMA (American Medical Association) Style

John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. EJMCR. 2022; 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558

Vancouver/ICMJE Style

John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. EJMCR. (2022), [cited December 25, 2024]; 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558

Harvard Style

John Swayne, Ritienne Debono, Maria Bonello (2022) Case report of an unusual manifestation of anti-GBM disease. EJMCR, 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558

Chicago Style

John Swayne, Ritienne Debono, Maria Bonello. "Case report of an unusual manifestation of anti-GBM disease." 22 (2022), 169-172. doi:10.24911/ejmcr/173-1660205558

MLA (The Modern Language Association) Style

John Swayne, Ritienne Debono, Maria Bonello. "Case report of an unusual manifestation of anti-GBM disease." 22.December 2022 (2022), 169-172. Print. doi:10.24911/ejmcr/173-1660205558

APA (American Psychological Association) Style

John Swayne, Ritienne Debono, Maria Bonello (2022) Case report of an unusual manifestation of anti-GBM disease. , 22 (December 2022), 169-172. doi:10.24911/ejmcr/173-1660205558