Case Report
Volume: 6 | Issue: 9 | Published: Dec 22, 2022 | Pages: 169 - 172 | DOI: 10.24911/ejmcr/173-1660205558
Case report of an unusual manifestation of anti-GBM disease
Authors: John Swayne , Ritienne Debono , Maria Bonello
Article Info
Authors
John Swayne
Department of Medicine, Division of Nephrology, Mater Dei Hospital, San Gwann, Malta
Ritienne Debono
Department of Medicine, Division of Nephrology, Mater Dei Hospital, San Gwann, Malta
Maria Bonello
Department of Neurology, Mater Dei Hospital, San Gwann, Malta.
Publication History
Received: August 27, 2022
Revised: November 28, 2022
Accepted: November 28, 2022
Published: December 22, 2022
Abstract
Background: Anti-GBM disease is a small vessel vasculitis that occurs when circulating antibodies against the glomerular basement membrane develop. It is a relatively rare disease, occurring in less than two cases per million population. The usual presentation is with renal or lung manifestations or with a combination of both. Case Presentation: Our case reports a patient who presented with end-stage renal disease secondary to anti-GBM disease, with no pulmonary manifestations, who later presented with a syndrome suggesting cerebral vasculitis, that responded to immunosuppressive treatment. Conclusion: Cerebral involvement in anti-GBM disease is very rare and to our knowledge, only a few cases have been so far reported.
Keywords: Anti-GBM disease, cerebral vasculitis, immunosuppression, small vessel vasculitis, green
Pubmed Style
John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. EJMCR. 2022; 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558
Web Style
John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. https://ejmcr.com/articles/1108 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1660205558
AMA (American Medical Association) Style
John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. EJMCR. 2022; 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558
Vancouver/ICMJE Style
John Swayne, Ritienne Debono, Maria Bonello. Case report of an unusual manifestation of anti-GBM disease. EJMCR. (2022), [cited December 25, 2024]; 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558
Harvard Style
John Swayne, Ritienne Debono, Maria Bonello (2022) Case report of an unusual manifestation of anti-GBM disease. EJMCR, 22 (December 2022): 169-172. doi:10.24911/ejmcr/173-1660205558
Chicago Style
John Swayne, Ritienne Debono, Maria Bonello. "Case report of an unusual manifestation of anti-GBM disease." 22 (2022), 169-172. doi:10.24911/ejmcr/173-1660205558
MLA (The Modern Language Association) Style
John Swayne, Ritienne Debono, Maria Bonello. "Case report of an unusual manifestation of anti-GBM disease." 22.December 2022 (2022), 169-172. Print. doi:10.24911/ejmcr/173-1660205558
APA (American Psychological Association) Style
John Swayne, Ritienne Debono, Maria Bonello (2022) Case report of an unusual manifestation of anti-GBM disease. , 22 (December 2022), 169-172. doi:10.24911/ejmcr/173-1660205558