EJMCR |

Case Report

Volume: 6 | Issue: 3 | Published: Apr 12, 2022 | Pages: 48 - 51 | DOI: 10.24911/ejmcr/173-1637238300

Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report

Authors: Raquel Fontes , Jorge Rodrigues , Camila Oliveira , Mauricio Peixoto , Ricardo Fernandes , Luisa Queiroz , Catarina Portela , Marta Almeida , Rui Nabico

Article Info

Authors

Raquel Fontes

Medical Oncology, Hospital of Braga, Braga, Portugal

ORCID

Jorge Rodrigues

Medical Oncology, Hospital of Braga, Braga, Portugal

Camila Oliveira

Medical Oncology, Hospital of Braga, Braga, Portugal

Mauricio Peixoto

Medical Oncology, Hospital of Braga, Braga, Portugal

Ricardo Fernandes

Medical Oncology, Hospital of Braga, Braga, Portugal

Luisa Queiroz

Medical Oncology, Hospital of Braga, Braga, Portugal

Catarina Portela

Medical Oncology, Hospital of Braga, Braga, Portugal

Marta Almeida

Medical Oncology, Hospital of Braga, Braga, Portugal

Rui Nabico

Medical Oncology, Hospital of Braga, Braga, Portugal.

Publication History

Received: November 21, 2021

Revised: March 11, 2022

Accepted: March 11, 2022

Published: April 12, 2022

Abstract

Background: Trastuzumab is a widely used and well-tolerated drug. Pulmonary toxicity has been described; however, the low incidence, the variability at presentation, and the nonspecific characteristics often make it an exclusion diagnosis. Case presentation: We present the case of a 62-year-old women admitted to our service with fever and shortness of breast after treatment with trastuzumab. From the study performed, no other cause was found to explain the event and the patient kept worsening until the diagnosis was established. Conclusion: Although pneumonitis is a rare side effect of trastuzumab administration, early recognition and appropriate therapy are crucial and may be lifesaving.

Keywords: breast cancer, trastuzumab, adverse reactions, pulmonary toxicity, case report, green

Pubmed Style

Raquel Fontes, Jorge Rodrigues, Camila Oliveira, Mauricio Peixoto, Ricardo Fernandes, Luisa Queiroz, Catarina Portela, Marta Almeida, Rui Nabico. Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report. EJMCR. 2022; 12 (April 2022): 48-51. doi:10.24911/ejmcr/173-1637238300

Web Style

Raquel Fontes, Jorge Rodrigues, Camila Oliveira, Mauricio Peixoto, Ricardo Fernandes, Luisa Queiroz, Catarina Portela, Marta Almeida, Rui Nabico. Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report. https://ejmcr.com/articles/1085 [Access: December 25, 2024]. doi:10.24911/ejmcr/173-1637238300

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Raquel Fontes, Jorge Rodrigues, Camila Oliveira, Mauricio Peixoto, Ricardo Fernandes, Luisa Queiroz, Catarina Portela, Marta Almeida, Rui Nabico. Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report. EJMCR. (2022), [cited December 25, 2024]; 12 (April 2022): 48-51. doi:10.24911/ejmcr/173-1637238300

Harvard Style

Raquel Fontes, Jorge Rodrigues, Camila Oliveira, Mauricio Peixoto, Ricardo Fernandes, Luisa Queiroz, Catarina Portela, Marta Almeida, Rui Nabico (2022) Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report. EJMCR, 12 (April 2022): 48-51. doi:10.24911/ejmcr/173-1637238300

Chicago Style

Raquel Fontes, Jorge Rodrigues, Camila Oliveira, Mauricio Peixoto, Ricardo Fernandes, Luisa Queiroz, Catarina Portela, Marta Almeida, Rui Nabico. "Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report." 12 (2022), 48-51. doi:10.24911/ejmcr/173-1637238300

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Raquel Fontes, Jorge Rodrigues, Camila Oliveira, Mauricio Peixoto, Ricardo Fernandes, Luisa Queiroz, Catarina Portela, Marta Almeida, Rui Nabico (2022) Toxic pneumonitis induced by trastuzumab as a potentially fatal event: a case report. , 12 (April 2022), 48-51. doi:10.24911/ejmcr/173-1637238300