Case Report

Volume: 5 | Issue: 3 | Published: Mar 24, 2021 | Pages: 71 - 75 | DOI: 10.24911/ejmcr/173-1595858983

A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points


Authors: David Mathew , Urmi Gupta , Uchechi Igbokwe , Sophie Todd , Paul Greaves , Teresa Doherty


Article Info

Authors

David Mathew

Barking, Havering and Redbridge University Trust, Rom Valley Way, Romford, United Kingdom

Urmi Gupta

Barking, Havering and Redbridge University Trust, Rom Valley Way, Romford, United Kingdom

Uchechi Igbokwe

Barking, Havering and Redbridge University Trust, Rom Valley Way, Romford, United Kingdom

Sophie Todd

Barking, Havering and Redbridge University Trust, Rom Valley Way, Romford, United Kingdom

Paul Greaves

Barking, Havering and Redbridge University Trust, Rom Valley Way, Romford, United Kingdom

Teresa Doherty

Barking, Havering and Redbridge University Trust, Rom Valley Way, Romford, United Kingdom

Publication History

Received: July 27, 2020

Revised: December 14, 2020

Accepted: January 02, 2021

Published: March 24, 2021


Abstract


Background: Adult Onset Stills Disease (AOSD) and Kikuchi Fujimoto Lymphadenitis (KFL) are both rare Rheumatological diseases. Co-occurrence is very rare. Case Presentation: This is a case of AOSD and KFL co-occurrence presenting with polyarthritis, rash, and B Symptoms. Elevated serum lactate dehydrogenase and ferritin with anemia and lymphadenopathy raised suspicions of lymphoma. Histology confirmed KFL and clinical features, and raised ferritin confirmed AOSD. After starting sulfasalazine, the patient was admitted to the hospital with ‘Drug Reaction with Eosinophilia and Systemic Symptoms’ (DRESS) Syndrome. Prior to sepsis exclusion, Gentamicin was given and subsequent hearing loss was noted. Sustained remission was achieved with Tocilizumab and azathioprine. Tocilizumab was stopped during pregnancy. Conclusion: The diagnostic challenges of two rare overlapping Rheumatological diseases are highlighted. An early distinction of disease flares or drug reactions from sepsis is difficult. Risk-benefit ratio consideration of continuing successful treatments in pregnancy is acknowledged.

Keywords: Case report, adult onset still disease, Kikuchi Fujimoto lymphadenitis, green


Pubmed Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty. A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points. EJMCR. 2021; 24 (March 2021): 71-75. doi:10.24911/ejmcr/173-1595858983

Web Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty. A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points. https://ejmcr.com/articles/1344 [Access: November 23, 2024]. doi:10.24911/ejmcr/173-1595858983

AMA (American Medical Association) Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty. A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points. EJMCR. 2021; 24 (March 2021): 71-75. doi:10.24911/ejmcr/173-1595858983

Vancouver/ICMJE Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty. A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points. EJMCR. (2021), [cited November 23, 2024]; 24 (March 2021): 71-75. doi:10.24911/ejmcr/173-1595858983

Harvard Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty (2021) A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points. EJMCR, 24 (March 2021): 71-75. doi:10.24911/ejmcr/173-1595858983

Chicago Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty. "A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points." 24 (2021), 71-75. doi:10.24911/ejmcr/173-1595858983

MLA (The Modern Language Association) Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty. "A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points." 24.March 2021 (2021), 71-75. Print. doi:10.24911/ejmcr/173-1595858983

APA (American Psychological Association) Style

David Mathew, Urmi Gupta, Uchechi Igbokwe, Sophie Todd, Paul Greaves, Teresa Doherty (2021) A case report of Adult Onset Still's Disease and Kikuchi Fujimoto lymphadenitischallenges and learning points. , 24 (March 2021), 71-75. doi:10.24911/ejmcr/173-1595858983