Case Report
Volume: 1 | Issue: 2 | Published: Jan 01, 1970 | Pages: 86 - 91 | DOI: 10.24911/ejmcr/1/21
Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report
Authors: Amybel Belladonna Taylor , May Lynn Yeap , Peta Sharples , Mohamed Osman Eltahir Babiker
Article Info
Authors
Amybel Belladonna Taylor
Department of Paediatric Neurology, Bristol Royal Hospital for Children, Bristol, UK
May Lynn Yeap
Department of Paediatric Neurology, Bristol Royal Hospital for Children, Bristol, UK
Peta Sharples
Department of Paediatric Neurology, Bristol Royal Hospital for Children, Bristol, UK
Mohamed Osman Eltahir Babiker
Faculty of Medicine, University of Bristol, Bristol, UK.
Publication History
Received: April 15, 2017
Accepted: May 10, 2017
Published: January 01, 1970
Abstract
Background: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome manifests as a significant, medication-induced, adverse reaction with cutaneous, hematological and multi-organ involvement. Sero-negative autoimmune encephalitis is inflammation of the brain secondary to autoimmune processes in the absence of an identifiable autoantibody. Case presentation: We present a pediatric case of sero-negative autoimmune encephalitis who subsequently developed DRESS syndrome as a result of exposure to ceftriaxone, omeprazole or acyclovir. She did not respond to either high-dose steroids or intravenous immunoglobulins (IVIG). Plasmapheresis was successful in treating symptoms relevant to both DRESS and sero-negative autoimmune encephalitis. No side effects were encountered. Conclusion: To our knowledge, plasmapheresis has only been reported once to treat DRESS syndrome in a pediatric patient. Early recognition and treatment of this syndrome is paramount. We suggest that plasmapheresis is a relatively safe alternative treatment option for resistant cases especially within the context of other autoimmune conditions.
Keywords: Plasmapharesis, DRESS syndrome, ceftriaxone, omeprazole, aciclovir, sero--negative autoimmune encephalitis, case report, green
Pubmed Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker. Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report. EJMCR. 1970; 01 (January 1970): 86-91. doi:10.24911/ejmcr/1/21
Web Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker. Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report. https://ejmcr.com/articles/1533 [Access: December 03, 2024]. doi:10.24911/ejmcr/1/21
AMA (American Medical Association) Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker. Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report. EJMCR. 1970; 01 (January 1970): 86-91. doi:10.24911/ejmcr/1/21
Vancouver/ICMJE Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker. Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report. EJMCR. (1970), [cited December 03, 2024]; 01 (January 1970): 86-91. doi:10.24911/ejmcr/1/21
Harvard Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker (1970) Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report. EJMCR, 01 (January 1970): 86-91. doi:10.24911/ejmcr/1/21
Chicago Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker. "Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report." 01 (1970), 86-91. doi:10.24911/ejmcr/1/21
MLA (The Modern Language Association) Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker. "Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report." 01.January 1970 (1970), 86-91. Print. doi:10.24911/ejmcr/1/21
APA (American Psychological Association) Style
Amybel Belladonna Taylor, May Lynn Yeap, Peta Sharples, Mohamed Osman Eltahir Babiker (1970) Successful treatment of DRESS syndrome with plasmapheresis during the course of sero-negative autoimmune encephalitis: a case report. , 01 (January 1970), 86-91. doi:10.24911/ejmcr/1/21