EJMCR |

Case Report

Volume: 1 | Issue: 1 | Published: May 24, 2017 | Pages: 48 - 51 | DOI: 10.24911/ejmcr/1/12

Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report

Authors: Ebtisam A Bakhsh , Reem A Alkhathami , Shazia Mukaddam , Ohoud Alarfaj

Authors

Ebtisam A Bakhsh

Princess Nourah Bint Abdulrahman University, faculty of Medicine, Clinical Sciences Department, Riyadh, 11671, Saudi Arabia

Reem A Alkhathami

King Fahad Medical City, Medical Specialties, Riyadh 11525, Saudi Arabia.

Shazia Mukaddam

King Fahad Medical City, Medical Specialties, Riyadh 11525, Saudi Arabia.

Ohoud Alarfaj

King Fahad Medical City, Pharmacy administration Riyadh, Saudi Arabia.

Publication History

Received: May 24, 2017

Accepted: January 01, 1970

Published: May 24, 2017

Abstract

Background: Antiphospholipid syndrome is a prothrombotic state characterized by the existence of persistent antiphospholipid antibodies. The key sequence of events is focal microthrombosis and post-infarction hemorrhage in the adrenal glands. Use of anticoagulant therapy is often used as a prevention and treatment among patients. Case presentation: We describe a case of 40 year old female who visited Emergency Room with complain of severe right upper quadrant pain for two days associated with nausea and vomiting. Initial laboratory investigations of blood, liver, and renal functions were normal. CT scan of abdomen revealed diffused enlargement of the right adrenal gland and showed relatively less enhancement indicating hemorrhage at the right side which later developed bilateral during admission. A day after admission, platelet count was 60,000 accompanied with worsened abdominal pain lead to diagnosis of catastrophic Anti-phospholipid syndrome (APLS). Conclusion: APS may lead to a variety of clinical manifestations due to venous and/or arterial thrombosis, so prescribing novel anticoagulants for patients with the APS is selective, and multiple factors are needed to be considered for a successful treatment.

Keywords: Antiphospholipid syndrome, adrenal hemorrhage, case report, anticoagulant therapy, bilateral hemorrhage, adrenal insufficiency, green

Pubmed Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR. 2017; 24 (May 2017): 48-51. doi:10.24911/ejmcr/1/12

Web Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. https://ejmcr.com/articles/1550 [Access: December 25, 2024]. doi:10.24911/ejmcr/1/12

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR. (2017), [cited December 25, 2024]; 24 (May 2017): 48-51. doi:10.24911/ejmcr/1/12

Harvard Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj (2017) Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report. EJMCR, 24 (May 2017): 48-51. doi:10.24911/ejmcr/1/12

Chicago Style

Ebtisam A Bakhsh, Reem A Alkhathami, Shazia Mukaddam, Ohoud Alarfaj. "Bilateral adrenal hemorrhage in APLS (anti-phospholipid syndrome) patient on Novel Anticoagulant: a case report." 24 (2017), 48-51. doi:10.24911/ejmcr/1/12