Case Report
Published: May 16, 2025 | DOI: 10.24911/ejmcr.9-1618
The Delineating CNS demyelinating disease: a case report
Authors:
Dr Deepinder Kaur Maini
, Dr Rajiv Anand
, Dr Shashank Raj
, Dr Varun Rehani
Article Info
Authors
Dr Deepinder Kaur Maini
PhD Scholar, Department of Neurology, Dr BL Kapur Hospital, Pusa Road, New Delhi
Dr Rajiv Anand
Director, Department of Neurology, Dr BL Kapur Hospital, Pusa Road, New Delhi
Dr Shashank Raj
Consultant, Department of Radiology, Dr BL Kapur Hospital, Pusa Road, New Delhi
Dr Varun Rehani
Senor Consultant, Department of Neurology, Dr BL Kapur Hospital, Pusa Road, New Delhi
Publication History
Received: December 02, 2024
Accepted: April 14, 2025
Published: May 16, 2025
Abstract
Background: Brain and spine MRI in NMOSD is well described in the diagnostic criteria of Wingherchuk 2015 criteria. However, despite this the pattern of lesion remains incomprehensive.
Case presentation: We report the case of a 65-year-old female with acute onset of drowsiness, dysphagia, aphasia and respiratory distress. Brain and spine MRI showed extensive white matter lesions in subcortical area and cystic lytic patchy lesions in spine. Extensive blood work up was conclusive of anti AQP4 IgG positive suggestive of NMOSD.
Conclusion: The bilateral extensive white matter lesions (EWML) are rare presentation in NMO disorders which may mimic adult leukodystrophy. This feature can be considered as a radiological marker for future references.
Keywords: NMOSD, CNS demyelinating disease, AQ4 positive,
Pubmed Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani. The Delineating CNS demyelinating disease: a case report. EJMCR. 2025; 16 (May 2025): -. doi:10.24911/ejmcr.9-1618
Web Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani. The Delineating CNS demyelinating disease: a case report. https://ejmcr.com/articles/1618 [Access: May 19, 2025]. doi:10.24911/ejmcr.9-1618
AMA (American Medical Association) Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani. The Delineating CNS demyelinating disease: a case report. EJMCR. 2025; 16 (May 2025): -. doi:10.24911/ejmcr.9-1618
Vancouver/ICMJE Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani. The Delineating CNS demyelinating disease: a case report. EJMCR. (2025), [cited May 19, 2025]; 16 (May 2025): -. doi:10.24911/ejmcr.9-1618
Harvard Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani (2025) The Delineating CNS demyelinating disease: a case report. EJMCR, 16 (May 2025): -. doi:10.24911/ejmcr.9-1618
Chicago Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani. "The Delineating CNS demyelinating disease: a case report." 16 (2025), -. doi:10.24911/ejmcr.9-1618
MLA (The Modern Language Association) Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani. "The Delineating CNS demyelinating disease: a case report." 16.May 2025 (2025), -. Print. doi:10.24911/ejmcr.9-1618
APA (American Psychological Association) Style
Dr Deepinder Kaur Maini, Dr Rajiv Anand, Dr Shashank Raj, Dr Varun Rehani (2025) The Delineating CNS demyelinating disease: a case report. , 16 (May 2025), -. doi:10.24911/ejmcr.9-1618