EJMCR |

Case Report

Volume: 8 | Issue: 4 | Published: May 03, 2024 | Pages: 77 - 81 | DOI: 10.24911/ejmcr.173-1712255577

A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens

Authors: Hena Parvin , Anwesha Dutta , Subhrajit Hazra

Article Info

Authors

Hena Parvin

Junior resident doctor Apollo Multispeciality Hospitals, West Bengal, India

Anwesha Dutta

Junior resident doctor Apollo Multispeciality Hospitals, West Bengal, India

Subhrajit Hazra

Consultant Radiologist, Apollo Multispeciality Hospitals, West Bengal, India.

Publication History

Received: April 05, 2024

Revised: October 08, 2024

Accepted: April 14, 2024

Published: May 03, 2024

Abstract

Background: Creutzfeldt Jacob disease is a rapidly progressive neurodegenerative disorder, which is invariably fatal and results in death within 1 year of onset. Patient presents with a variety of non-specific neuropsychiatric symptoms, like myoclonus, cerebellar symptoms, visual impairment, and behavioural abnormalities. The symptoms are rapidly progressive and cause early functional impairment in the patient. Case presentation: In this report, we discussed a case of 49 years old male presented with multiple neuropsychiatric symptoms. After a series of extensive diagnostic examinations and follow-up, the patient was diagnosed as probable sporadic Creutzfeldt-Jakob disease based on 2018 Centres for Disease Control and Prevention (CDC) criteria, with key findings of myoclonus, behavioural and cerebellar problems, visual abnormalities, abnormal hyperintensity signals on diffusion-weighted MRI and characteristic EEG waves. CSF 14-3-3 protein was significantly high. Conclusion: Sporadic CJD is a rare and fatal rapidly progressive neurodegenerative disorder, which claims prompt and precise diagnosis to help the clinicians in distinguishing it from potentially treatable neuropsychiatric disorders. This aspect elevates the significance of our report, as it aids not only the medical professionals but also the affected families. Early diagnosis enables family to prepare for disease course and appropriate management strategies.

Keywords: case report, sporadic Creutzfeldt-Jakob disease, prion disease, rapidly progressing dementia, fatal neurodegenerative disorder, green

Pubmed Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra. A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens. EJMCR. 2024; 03 (May 2024): 77-81. doi:10.24911/ejmcr.173-1712255577

Web Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra. A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens. https://ejmcr.com/articles/1245 [Access: December 25, 2024]. doi:10.24911/ejmcr.173-1712255577

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra. A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens. EJMCR. (2024), [cited December 25, 2024]; 03 (May 2024): 77-81. doi:10.24911/ejmcr.173-1712255577

Harvard Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra (2024) A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens. EJMCR, 03 (May 2024): 77-81. doi:10.24911/ejmcr.173-1712255577

Chicago Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra. "A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens." 03 (2024), 77-81. doi:10.24911/ejmcr.173-1712255577

MLA (The Modern Language Association) Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra. "A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens." 03.May 2024 (2024), 77-81. Print. doi:10.24911/ejmcr.173-1712255577

APA (American Psychological Association) Style

Hena Parvin, Anwesha Dutta, Subhrajit Hazra (2024) A case report on Creutzfeldt-Jacob Disease: Early diagnosis through multidisciplinary lens. , 03 (May 2024), 77-81. doi:10.24911/ejmcr.173-1712255577