Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report
Authors: Iftikhar Ahmad, Mehjabeen Marri, Sadaf Noor
Background: Extra-nodal diffuse large B-cell lymphoma (DLBCL) is an exceedingly uncommon disease. Case Presentation: Herein, we report a case of a 60-year-old male patient who presented with DLBCL of the left leg, and involving the gastrocnemius muscle. The patient received CHOP regimen-based neoadjuvant chemotherapy (i.e., six courses of cyclophosphamide, doxorubicin, vincristine, and prednisone), which reduced the tumor size to the point where complete resection became possible. Afterward, the tumor was completely resected. The tumor bed subsequently received conventional radiotherapy (i.e., 36 Gy/18 fractions). The patient is being followed up regularly and has remained disease-free for over 1.5 years. Conclusion: This case demonstrates that DLBCL is an aggressive malignancy but can be effectively managed with multi-modality treatment strategy.
Keywords: Diffuse large B-cell lymphoma, CHOP regimen, R-CHOP regimen, non-Hodgkins lymphoma, radiotherapy
Authors
Correspondence to:
Iftikhar Ahmad, Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan iahmadmp@gmail.com
Publication history:
Received 01 Jan 2020
Revised 10 Mar 2020
Accepted 27 Mar 2020
Published in print 04 Apr 2020
Ahmad I, Marri M, Noor S. Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. EJMCR. 2020; 4(3): 103-106. doi:
10.24911/ejmcr/1731577849668
Ahmad I, Marri M, Noor S. Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. https://www.ejmcr.com/?mno=80154 [Access: May 11, 2024]. doi:
10.24911/ejmcr/1731577849668
Ahmad I, Marri M, Noor S. Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. EJMCR. 2020; 4(3): 103-106. doi:
10.24911/ejmcr/1731577849668
Ahmad I, Marri M, Noor S. Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. EJMCR. (2020), [cited May 11, 2024]; 4(3): 103-106. doi:
10.24911/ejmcr/1731577849668
Ahmad, I., Marri, . M. & Noor, . S. (2020) Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. EJMCR, 4 (3), 103-106. doi:
10.24911/ejmcr/1731577849668
Ahmad, Iftikhar, Mehjabeen Marri, and Sadaf Noor. 2020. Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. European Journal of Medical Case Reports, 4 (3), 103-106. doi:
10.24911/ejmcr/1731577849668
Ahmad, Iftikhar, Mehjabeen Marri, and Sadaf Noor. "Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report." European Journal of Medical Case Reports 4 (2020), 103-106. doi:
10.24911/ejmcr/1731577849668
Ahmad, Iftikhar, Mehjabeen Marri, and Sadaf Noor. "Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report." European Journal of Medical Case Reports 4.3 (2020), 103-106. Print. doi:
10.24911/ejmcr/1731577849668
Ahmad, I., Marri, . M. & Noor, . S. (2020) Diffuse large B-cell lymphoma of the leg involving the gastrocnemius muscles: a case report. European Journal of Medical Case Reports, 4 (3), 103-106. doi:
10.24911/ejmcr/1731577849668