Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus
Authors: Poh Sen Tay, Phyllis Wan Chun Ho
Background: Acute necrotizing encephalopathy of childhood (ANEC) is a rare but distinctive type of encephalopathy predominantly involving infants and young children. This case report describes the characteristic neuroimaging findings which can aid in early diagnosis of ANEC. Case Presentation: An 11-year-old boy presented with a 2-day history of fever and flu-like illness and was given symptomatic treatment. He subsequently deteriorated on day 3 of illness with generalized tonic-clonic seizure and impaired consciousness. Magnetic resonance imaging done revealed abnormal signal intensities at bilateral thalami, brainstem, and cerebellum, which are suggestive of ANEC, correlating with his clinical presentation. Treatment was started immediately, but the patient had a very poor recovery. Conclusion: ANEC is a very rare encephalopathy and has very high mortality and morbidity with severe neurologic sequelae. Early diagnosis is important so that appropriate management can be provided.
Keywords: Case report, acute necrotizing encephalopathy of childhood (ANEC), influenza A, H1N1.
Authors
Correspondence to:
Poh Sen Tay, Radiologist, Sarawak General Hospital, Jalan Hospital, Sarawak, Malaysia pohsen@gmail.com
Publication history:
Received 25 Nov 2019
Revised 20 Aug 2020
Accepted 14 Sep 2020
Published online 14 Oct 2020
Published in print 17 Oct 2020
Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR. 2020; 4(9): 292-295. doi:
10.24911/ejmcr/173-1574570790
Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. https://www.ejmcr.com/?mno=75047 [Access: May 13, 2024]. doi:
10.24911/ejmcr/173-1574570790
Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR. 2020; 4(9): 292-295. doi:
10.24911/ejmcr/173-1574570790
Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR. (2020), [cited May 13, 2024]; 4(9): 292-295. doi:
10.24911/ejmcr/173-1574570790
Tay, P. S. & Ho, . P. W. C. (2020) Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR, 4 (9), 292-295. doi:
10.24911/ejmcr/173-1574570790
Tay, Poh Sen, and Phyllis Wan Chun Ho. 2020. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. European Journal of Medical Case Reports, 4 (9), 292-295. doi:
10.24911/ejmcr/173-1574570790
Tay, Poh Sen, and Phyllis Wan Chun Ho. "Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus." European Journal of Medical Case Reports 4 (2020), 292-295. doi:
10.24911/ejmcr/173-1574570790
Tay, Poh Sen, and Phyllis Wan Chun Ho. "Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus." European Journal of Medical Case Reports 4.9 (2020), 292-295. Print. doi:
10.24911/ejmcr/173-1574570790
Tay, P. S. & Ho, . P. W. C. (2020) Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. European Journal of Medical Case Reports, 4 (9), 292-295. doi:
10.24911/ejmcr/173-1574570790